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Last Updated: November 2, 2024

CLINICAL TRIALS PROFILE FOR GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE


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All Clinical Trials for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00000752 ↗ Preventing Frequent Sinus Infections in HIV-Infected Patients Withdrawn Adams Laboratories Phase 2 1969-12-31 To evaluate the additional effectiveness of an anti-inflammatory nasal spray ( beclomethasone dipropionate ) and a broad spectrum antibiotic ( cefuroxime axetil ) over decongestant ( Deconsal II ) alone, when these agents are given individually or in combination for the prevention of recurrent paranasal sinus infection in patients with HIV infection. To compare the clinical utility of paranasal sinus radiographs with computed tomograms (CTs) in the evaluation and management of HIV-infected patients with recurrent paranasal sinus infection. To determine relevant prognostic factors and the microbiologic etiology of maxillary sinusitis in this patient population. Sinusitis is common among HIV-infected patients and is likely to be recurrent or refractory to traditional therapy, particularly in patients with advanced immunosuppression. An intervention aimed at prevention of recurrent sinus disease in HIV-infected patients appears to be warranted.
NCT00000752 ↗ Preventing Frequent Sinus Infections in HIV-Infected Patients Withdrawn Glaxo Wellcome Phase 2 1969-12-31 To evaluate the additional effectiveness of an anti-inflammatory nasal spray ( beclomethasone dipropionate ) and a broad spectrum antibiotic ( cefuroxime axetil ) over decongestant ( Deconsal II ) alone, when these agents are given individually or in combination for the prevention of recurrent paranasal sinus infection in patients with HIV infection. To compare the clinical utility of paranasal sinus radiographs with computed tomograms (CTs) in the evaluation and management of HIV-infected patients with recurrent paranasal sinus infection. To determine relevant prognostic factors and the microbiologic etiology of maxillary sinusitis in this patient population. Sinusitis is common among HIV-infected patients and is likely to be recurrent or refractory to traditional therapy, particularly in patients with advanced immunosuppression. An intervention aimed at prevention of recurrent sinus disease in HIV-infected patients appears to be warranted.
NCT00000752 ↗ Preventing Frequent Sinus Infections in HIV-Infected Patients Withdrawn National Institute of Allergy and Infectious Diseases (NIAID) Phase 2 1969-12-31 To evaluate the additional effectiveness of an anti-inflammatory nasal spray ( beclomethasone dipropionate ) and a broad spectrum antibiotic ( cefuroxime axetil ) over decongestant ( Deconsal II ) alone, when these agents are given individually or in combination for the prevention of recurrent paranasal sinus infection in patients with HIV infection. To compare the clinical utility of paranasal sinus radiographs with computed tomograms (CTs) in the evaluation and management of HIV-infected patients with recurrent paranasal sinus infection. To determine relevant prognostic factors and the microbiologic etiology of maxillary sinusitis in this patient population. Sinusitis is common among HIV-infected patients and is likely to be recurrent or refractory to traditional therapy, particularly in patients with advanced immunosuppression. An intervention aimed at prevention of recurrent sinus disease in HIV-infected patients appears to be warranted.
NCT01085721 ↗ Comparison Between Dexchlorpheniramine and Dexchlorpheniramine/Pseudoephedrine/Guaifenesin in Respiratory Infections Unknown status Mantecorp Industria Quimica e Farmaceutica Ltd. Phase 3 1969-12-31 Patients with allergic rhinitis frequently present exacerbation of the atopic symptoms during viral infections of the upper respiratory tract. Also, allergic rhinitis makes the mucosa more reactive to infectious agents and potentiates mucus production. The combination of dexchlorpheniramine, pseudoephedrine and guaifenesin elicits antihistaminic, decongestant and expectorant effects. The study hypothesizes is that this product is superior to dexchlorpheniramine alone in the relief of allergic symptoms and in promoting mucus elimination in atopic patients with viral infections of the upper respiratory tract.
NCT01202279 ↗ Safety and Efficacy Study of Guaifenesin and Pseudoephedrine for Symptomatic Therapy to Treat Acute RTI Completed Reckitt Benckiser Inc. Phase 4 2009-10-01 The purpose of this study is to determine if treatment with Mucinex D lowers the use of antibiotics in the treatment of upper respiratory infection when compared to placebo
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE

Condition Name

Condition Name for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Intervention Trials
HIV Infections 1
Sinusitis 1
Viral Infections of the Upper Respiratory Tract 1
Acute Upper Respiratory Track Infection 1
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Condition MeSH

Condition MeSH for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Intervention Trials
Infections 3
Infection 2
Respiratory Tract Infections 1
Communicable Diseases 1
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Clinical Trial Locations for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE

Trials by Country

Trials by Country for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Location Trials
United States 21
India 1
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Trials by US State

Trials by US State for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Location Trials
Pennsylvania 2
California 2
South Carolina 1
Oregon 1
Oklahoma 1
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Clinical Trial Progress for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE

Clinical Trial Phase

Clinical Trial Phase for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Clinical Trial Phase Trials
Phase 4 1
Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Clinical Trial Phase Trials
Completed 2
Unknown status 1
Withdrawn 1
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Clinical Trial Sponsors for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE

Sponsor Name

Sponsor Name for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Sponsor Trials
Mantecorp Industria Quimica e Farmaceutica Ltd. 1
Reckitt Benckiser Inc. 1
Reckitt Benckiser LLC 1
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Sponsor Type

Sponsor Type for GUAIFENESIN; PSEUDOEPHEDRINE HYDROCHLORIDE
Sponsor Trials
Industry 6
NIH 1
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