Combination of Halobetasol Propionate and Tazarotene Lotion (Duobrii®) for Palmoplantar Plaque Type Psoriasis
Recruiting
Bausch Health Americas, Inc.
Phase 4
2020-11-19
The purpose of this research study is to examine the effect of Duobrii® (halobetasol
propionate 0.01%/tazarotene 0.045% lotion, HP/TAZ) on plaque type psoriasis of the hands
and/or feet.
Combination of Halobetasol Propionate and Tazarotene Lotion (Duobrii®) for Palmoplantar Plaque Type Psoriasis
Recruiting
Icahn School of Medicine at Mount Sinai
Phase 4
2020-11-19
The purpose of this research study is to examine the effect of Duobrii® (halobetasol
propionate 0.01%/tazarotene 0.045% lotion, HP/TAZ) on plaque type psoriasis of the hands
and/or feet.
A Study Comparing Halobetasol Propionate and Tazarotene Topical Lotion 0.01%/0.045% to Duobrii® Lotion (Halobetasol Propionate and Tazarotene Lotion), 0.01%/0.045% (Reference Listed Drug) in the Treatment of Moderate to Severe Plaque Psoriasis.
Completed
Taro Pharmaceuticals USA
Early Phase 1
2021-04-16
To evaluate the therapeutic equivalence and safety of halobetasol propionate and tazarotene
topical lotion 0.01%/0.045% (Taro Pharmaceuticals U.S.A., Inc.) and Duobrii® Lotion
(halobetasol and tazarotene lotion), 0.01%/0.045% (Reference Listed Drug) in the treatment of
moderate to severe plaque psoriasis.
Anti-Inflammatory Effects of 0.045% Tazarotene/0.01% Halobetasol Lotion in Psoriasis
Completed
Dermatology Consulting Services, PLLC
Phase 4
2023-07-13
The objective of this research is to demonstrate superior anti-inflammatory effects, as
demonstrated by a reduction in TNF-a and IL-17A, with tazarotene/halobetasol lotion in
patients with mild to moderate plaque type psoriasis as compared to clobetasol propionate
0.05% cream.
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