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Last Updated: November 24, 2024

CLINICAL TRIALS PROFILE FOR IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE


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All Clinical Trials for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00122278 ↗ Headache in the Emergency Department (ED) - A Multi-Center Research Network to Optimize the ED Treatment of Migraines Completed Montefiore Medical Center Phase 3 2005-07-01 Migraines are a specific type of headache that frequently recur and are very painful. Although there are many medications that are effective against migraines, none of these medications cure 100% of migraines. Another problem with migraines is that although many times they get better after intravenous (IV) treatment in the emergency room (ER), about 1/3 of the time migraines recur the next day. The purpose of this research project is to see if adding a medication called dexamethasone to standard ER therapy will help patients get better quicker and stay pain-free more often than if they receive placebo.
NCT00129506 ↗ Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion Completed Ibis Reproductive Health Phase 4 2005-05-01 Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens. Methotrexate, which is used with misoprostol in Canada, is also difficult to obtain in many countries. Misoprostol is inexpensive and available in almost all countries. A report from Nigeria found that 98% of 100 women aborted within 24 hours of using misoprostol given both sublingually and vaginally. Method: This will be a randomized controlled trial of the usual regimen used in Canada, methotrexate 50 mg/m2 intramuscularly (IM) followed three days later by 800 mcg vaginal misoprostol to the Nigerian regimen of 400 mcg sublingual misoprostol with 400 mcg vaginal misoprostol. The main outcome measure will be a completed abortion within the first week with secondary outcome measures including total surgery rate, time to abortion, complications, pain, side effects and patient satisfaction. Rationale: If the investigators can find an inexpensive, easily available, method of medical abortion, it will save many lives in third world countries.
NCT00129506 ↗ Comparing Methotrexate Followed by Misoprostol to Misoprostol Alone for Early Abortion Completed Wiebe, Ellen, M.D. Phase 4 2005-05-01 Background: In most countries in which abortion is legal, medical abortions are induced with mifepristone and misoprostol. Since mifepristone is expensive and unavailable in many countries, it is important to find other regimens. Methotrexate, which is used with misoprostol in Canada, is also difficult to obtain in many countries. Misoprostol is inexpensive and available in almost all countries. A report from Nigeria found that 98% of 100 women aborted within 24 hours of using misoprostol given both sublingually and vaginally. Method: This will be a randomized controlled trial of the usual regimen used in Canada, methotrexate 50 mg/m2 intramuscularly (IM) followed three days later by 800 mcg vaginal misoprostol to the Nigerian regimen of 400 mcg sublingual misoprostol with 400 mcg vaginal misoprostol. The main outcome measure will be a completed abortion within the first week with secondary outcome measures including total surgery rate, time to abortion, complications, pain, side effects and patient satisfaction. Rationale: If the investigators can find an inexpensive, easily available, method of medical abortion, it will save many lives in third world countries.
NCT01014767 ↗ Intercontinental Multidisciplinary Registry and Treatment Optimization Study for Choroid Plexus Tumors Terminated Tufts Medical Center Phase 3 2009-11-01 This is a "tissue banking and data review" research study that also has a "clinical" research part: - The goal of the tissue banking part of this study is to store tissue in a research tissue bank by the International Society for Pediatric Oncology (SIOP) at an international reference center for choroid plexus tumors. The tissue will be used in future research related to cancer. - The goal of the data review part of this study is to collect information from the medical records of patients with choroid plexus tumors, and to store the information in SIOP databases for use in future research related to cancer. - The goal of this clinical research study is to compare 4 chemotherapy treatments for choroid plexus tumors. The safety and level of effectiveness of these study treatments will be compared and studied. The study drugs include different combinations of etoposide, carboplatin, vincristine, cyclophosphamide, methotrexate, doxorubicin, cisplatin, dactinomycin, temozolomide, and irinotecan.
NCT01053208 ↗ Bioequivalence Study of Dr.Reddy's Ibuprofen and Diphenhydramine Citrate 200 mg/38 mg Caplets Under Fasting Condition Completed Dr. Reddy's Laboratories Limited Phase 1 2008-04-01 To determine the single-dose oral bioequivalence study of Ibuprofen and Diphenhydramine citrate 200 mg/38 mg caplets of Dr. Reddy's Laboratories Limited, India and AdvilĀ® PM, of Wyeth consumer health care, USA, in normal, healthy, adult, human subjects under fasting conditions.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Condition Name

Condition Name for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Intervention Trials
Pain 2
Healthy 2
Refractory T Acute Lymphoblastic Leukemia 1
Migraine 1
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Condition MeSH

Condition MeSH for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Intervention Trials
Migraine Disorders 2
Headache 2
Precursor Cell Lymphoblastic Leukemia-Lymphoma 1
Pain, Postoperative 1
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Clinical Trial Locations for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Trials by Country

Trials by Country for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Location Trials
United States 7
India 2
Canada 1
New Zealand 1
China 1
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Trials by US State

Trials by US State for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Location Trials
California 1
Oregon 1
Connecticut 1
Utah 1
Texas 1
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Clinical Trial Progress for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Clinical Trial Phase

Clinical Trial Phase for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Clinical Trial Phase Trials
Phase 4 2
Phase 3 2
Phase 2/Phase 3 1
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Clinical Trial Status

Clinical Trial Status for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Clinical Trial Phase Trials
Completed 7
Not yet recruiting 2
Recruiting 1
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Clinical Trial Sponsors for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE

Sponsor Name

Sponsor Name for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Sponsor Trials
Dr. Reddy's Laboratories Limited 2
Oregon Health and Science University 1
National Cancer Institute (NCI) 1
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Sponsor Type

Sponsor Type for IBUPROFEN AND DIPHENHYDRAMINE HYDROCHLORIDE
Sponsor Trials
Other 9
Industry 6
NIH 1
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