Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer
Completed
National Cancer Institute (NCI)
Phase 3
2003-12-01
RATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who
are undergoing chemoradiotherapy for anal or rectal cancer. It is not yet known whether
octreotide is effective in treating diarrhea.
PURPOSE: This randomized phase III trial is studying octreotide in preventing or reducing
diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.
Octreotide in Preventing or Reducing Diarrhea in Patients Receiving Chemoradiotherapy for Anal or Rectal Cancer
Completed
Radiation Therapy Oncology Group
Phase 3
2003-12-01
RATIONALE: Octreotide may be effective in preventing or controlling diarrhea in patients who
are undergoing chemoradiotherapy for anal or rectal cancer. It is not yet known whether
octreotide is effective in treating diarrhea.
PURPOSE: This randomized phase III trial is studying octreotide in preventing or reducing
diarrhea in patients who are undergoing chemoradiotherapy for anal or rectal cancer.
Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea
Completed
Bausch Health Americas, Inc.
Phase 4
2004-06-01
Most cases of travelers' diarrhea are caused by bacterial pathogens which respond slowly to
antibiotic treatment.The study was designed to determine the value of rapidly acting
loperamide (imodium) combined with curative dose of the poorly absorbed rifaximin in
travelers' diarreha treatment.
Rifaximin, Loperamide and the Combination to Treat Travelers' Diarrhea
Completed
Valeant Pharmaceuticals International, Inc.
Phase 4
2004-06-01
Most cases of travelers' diarrhea are caused by bacterial pathogens which respond slowly to
antibiotic treatment.The study was designed to determine the value of rapidly acting
loperamide (imodium) combined with curative dose of the poorly absorbed rifaximin in
travelers' diarreha treatment.
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