Phase I-II Study of Fluorouracil in Combination With Phenylbutyrate in Advanced Colorectal Cancer
Terminated
National Cancer Institute (NCI)
Phase 1/Phase 2
1997-05-01
Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop
growing or die. Interferon-gamma may interfere with the growth of tumor cells and slow the
growth of the tumor. Combining more than one drug with interferon-gamma may kill more tumor
cells. This phase I/II trial is studying the side effects and best dose of giving
fluorouracil together with phenylbutyrate, indomethacin, and interferon-gamma and to see how
well it works in treating patients with stage IV colorectal cancer
A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer
Completed
Brooklyn ImmunoTherapeutics, LLC
Phase 2
2005-07-01
This was a Phase 2a trial to investigate the safety and biological activity of the RIX-2
Regimen in patients with untreated, resectable squamous cell cancer of the head and neck
(HNSCC).
A Phase 2 Clinical Trial of the Safety and Effects of IRX-2 in Treating Patients With Operable Head and Neck Cancer
Completed
IRX Therapeutics
Phase 2
2005-07-01
This was a Phase 2a trial to investigate the safety and biological activity of the RIX-2
Regimen in patients with untreated, resectable squamous cell cancer of the head and neck
(HNSCC).
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