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Last Updated: November 13, 2024

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CLINICAL TRIALS PROFILE FOR INQOVI


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All Clinical Trials for INQOVI

Trial ID Title Status Sponsor Phase Start Date Summary
NCT04093570 ↗ An Open-Label, Multicenter, Extension Study for Subjects Who Participated in Prior Clinical Studies of ASTX727 (Standard Dose) Enrolling by invitation Astex Pharmaceuticals, Inc. Phase 2 2019-09-30 Extension study for subjects who participated in a previous Astex-sponsored clinical study of ASTX727 (including, but not limited to ASTX727-01, ASTX727-02, ASTX727-04).
NCT04340843 ↗ Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional Chondrosarcoma Recruiting National Cancer Institute (NCI) Phase 2 2020-07-06 This phase II trial studies the effect of belinostat and SGI-110 (guadecitabine) or ASTX727 in treating patients with conventional chondrosarcoma that cannot be removed by surgery (unresectable) and has spread to other places in the body (metastatic). Belinostat may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Chemotherapy drugs, such as guadecitabine and ASTX727, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Giving belinostat in combination with guadecitabine or ASTX727 may lower the chance of unresectable and metastatic chondrosarcoma growing or spreading.
NCT04655755 ↗ Venetoclax in Combination With ASTX727 for the Treatment of Treatment-Naive High-Risk Myelodysplastic Syndrome or Chronic Myelomonocytic Leukemia Recruiting Astex Pharmaceuticals, Inc. Phase 1/Phase 2 2021-01-19 This phase I/II trial studies the side effects and best dose of venetoclax in combination with cedazuridine and decitabine (ASTX727) in treating patients with high risk myelodysplastic syndrome or chronic myelomonocytic leukemia who have not received prior treatment (treatment-naive). Chemotherapy drugs, such as venetoclax, cedazuridine, and decitabine, work in different ways to stop the growth of cancer cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for INQOVI

Condition Name

Condition Name for INQOVI
Intervention Trials
Acute Myeloid Leukemia 11
Recurrent Acute Myeloid Leukemia 5
Chronic Myelomonocytic Leukemia 5
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Condition MeSH

Condition MeSH for INQOVI
Intervention Trials
Leukemia 16
Leukemia, Myeloid 12
Leukemia, Myeloid, Acute 12
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Clinical Trial Locations for INQOVI

Trials by Country

Trials by Country for INQOVI
Location Trials
United States 51
Canada 1
Australia 1
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Trials by US State

Trials by US State for INQOVI
Location Trials
Texas 12
New York 5
California 4
Maryland 3
Illinois 3
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Clinical Trial Progress for INQOVI

Clinical Trial Phase

Clinical Trial Phase for INQOVI
Clinical Trial Phase Trials
Phase 2 9
Phase 1/Phase 2 7
Phase 1 9
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Clinical Trial Status

Clinical Trial Status for INQOVI
Clinical Trial Phase Trials
Not yet recruiting 11
Recruiting 11
Suspended 2
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Clinical Trial Sponsors for INQOVI

Sponsor Name

Sponsor Name for INQOVI
Sponsor Trials
National Cancer Institute (NCI) 10
M.D. Anderson Cancer Center 9
Astex Pharmaceuticals, Inc. 6
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Sponsor Type

Sponsor Type for INQOVI
Sponsor Trials
Other 20
Industry 10
NIH 10
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