CLINICAL TRIALS PROFILE FOR ISUPREL

All Clinical Trials for ISUPREL

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT02615119 ↗	Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa	Recruiting	National Institute of Mental Health (NIMH)	N/A	2015-10-01	This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or brain injury. By evaluating the same interoceptive sensations across different human illnesses, the investigators hope to provide convergent evidence resulting in identification of core underlying neural processes, and to discern relative contributions in each condition.
NCT02615119 ↗	Neural Basis of Meal Related Interoceptive Dysfunction in Anorexia Nervosa	Recruiting	Laureate Institute for Brain Research, Inc.	N/A	2015-10-01	This study aims to identify the brain regions responsible for encoding cardiorespiratory 'interoceptive' sensations and determine whether they are dysfunctional in individuals affected by eating disorders, anxiety, depression, or brain injury. By evaluating the same interoceptive sensations across different human illnesses, the investigators hope to provide convergent evidence resulting in identification of core underlying neural processes, and to discern relative contributions in each condition.
NCT02673996 ↗	POTS Adrenergic Ab (CIHR Aims #1&2)	Recruiting	University of Calgary		2016-01-01	Objective: In this pilot study, we will test the hypothesis that patients with POTS (age 18-60 years) will have a higher percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS.
NCT02725060 ↗	Autoimmune Basis for Postural Tachycardia Syndrome	Enrolling by invitation	University of Oklahoma	N/A	2016-02-01	The purpose of this study is to see if some people with postural tachycardia syndrome (POTS) have higher levels of immune proteins (autoantibodies) directed against receptors of the autonomic nervous system, and if these autoantibodies make a difference in their POTS symptoms. The investigators also want to see if the levels of these autoantibodies stay the same over time.
NCT02725060 ↗	Autoimmune Basis for Postural Tachycardia Syndrome	Enrolling by invitation	Vanderbilt University	N/A	2016-02-01	The purpose of this study is to see if some people with postural tachycardia syndrome (POTS) have higher levels of immune proteins (autoantibodies) directed against receptors of the autonomic nervous system, and if these autoantibodies make a difference in their POTS symptoms. The investigators also want to see if the levels of these autoantibodies stay the same over time.

Clinical Trial Conditions for ISUPREL

Condition Name

Condition Name for ISUPREL
Intervention	Trials
Postural Tachycardia Syndrome	2
Anorexia Nervosa	2
Arrhythmias, Cardiac	1
Primary Dysautonomias	1

Condition MeSH

Condition MeSH for ISUPREL
Intervention	Trials
Tachycardia	2
Syndrome	2
Postural Orthostatic Tachycardia Syndrome	2
Anorexia Nervosa	2

Clinical Trial Locations for ISUPREL

Trials by Country

Trials by Country for ISUPREL
Location	Trials
United States	5
Canada	1

Trials by US State

Trials by US State for ISUPREL
Location	Trials
Oklahoma	3
Michigan	1
Tennessee	1

Clinical Trial Progress for ISUPREL

Clinical Trial Phase

Clinical Trial Phase for ISUPREL
Clinical Trial Phase	Trials
Phase 2	1
N/A	3

Clinical Trial Status

Clinical Trial Status for ISUPREL
Clinical Trial Phase	Trials
Recruiting	2
Active, not recruiting	1
Completed	1

Clinical Trial Sponsors for ISUPREL

Sponsor Name

Sponsor Name for ISUPREL
Sponsor	Trials
Laureate Institute for Brain Research, Inc.	2
University of Calgary	1
University of Oklahoma	1

Sponsor Type

Sponsor Type for ISUPREL
Sponsor	Trials
Other	8
NIH	1