A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin
Unknown status
Clalit Health Services
Phase 3
2008-06-01
Comparison between the effectiveness of one anti-diabetic drug (Metformin, To combination of
this drug and additional drug (Janufer), In the community setting.
A Double-Blind, Randomized, Active-Comparator (Metformin) Controlled, Clinical Trial to Study the Efficacy and Safety of the Strategy to Start Patients With Type 2 Diabetes Mellitus on Janumet™ Compared to Metformin
Unknown status
Meir Medical Center
Phase 3
2008-06-01
Comparison between the effectiveness of one anti-diabetic drug (Metformin, To combination of
this drug and additional drug (Janufer), In the community setting.
Efficacy and Safety of Sitagliptin/Metformin Fixed-Dose Combination (FDC) Compared to Glimepiride in Participants With Type 2 Diabetes Mellitus (MK-0431A-202)
Completed
Merck Sharp & Dohme Corp.
Phase 4
2010-05-04
This study will assess the effect of sitagliptin/metformin FDC 50/1000 mg (Janumet®),
MK-0431A) compared with the effect of glimepiride on hemoglobin A1c (HbA1c). The primary
hypothesis is that after 30 weeks, sitagliptin/metformin FDC 50/1000 mg provides superior
reduction in HbA1c (mean change from baseline) compared to glimepiride.
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