CLINICAL TRIALS PROFILE FOR KEFLEX
✉ Email this page to a colleague
All Clinical Trials for KEFLEX
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00300092 ↗ | Pediatric Fingertip Injuries:Are Antibiotics Required? | Completed | Children's Hospital Los Angeles | Phase 2 | 2000-09-01 | Study objective: Fingertip injuries are common in the pediatric population. Considerable controversy exists about whether prophylactic antibiotics are necessary after repair of such injuries. Our goals were to estimate the rate of bacterial infection among pediatric patients with distal fingertip injuries overall and to compare the rate of bacterial infections among subgroups treated with and without prophylactic antibiotics. Methods: This was prospective randomized control study of pediatric patients presenting to an urban children's hospital with trauma to the distal fingertip requiring repair. Patients were randomized to two groups: those receiving prophylactic antibiotics (Cephalexin) and those who did not receive antibiotic therapy. Repairs were performed in a standardized fashion and all patients were re-evaluated in the same emergency department in 48 hours and by phone 7 days later. The primary outcome of this study was the incidence of infection. |
| NCT00352612 ↗ | Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections | Completed | Johns Hopkins University | Phase 4 | 2006-09-01 | The purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). The investigators hypothesize that treatment with cephalexin, a penicillin-like antibiotic to which CA-MRSA would be expected to be resistant, does not result in poorer outcomes than treatment with clindamycin, an antibiotic to which CA-MRSA is most often susceptible. |
| NCT00352612 ↗ | Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections | Completed | Thrasher Research Fund | Phase 4 | 2006-09-01 | The purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). The investigators hypothesize that treatment with cephalexin, a penicillin-like antibiotic to which CA-MRSA would be expected to be resistant, does not result in poorer outcomes than treatment with clindamycin, an antibiotic to which CA-MRSA is most often susceptible. |
| NCT00352612 ↗ | Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections | Completed | Aaron Chen | Phase 4 | 2006-09-01 | The purpose of this study is to help define the role of antibiotics in the treatment of pediatric skin infections caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA). The investigators hypothesize that treatment with cephalexin, a penicillin-like antibiotic to which CA-MRSA would be expected to be resistant, does not result in poorer outcomes than treatment with clindamycin, an antibiotic to which CA-MRSA is most often susceptible. |
| NCT00676130 ↗ | Study of New Antibiotic Regimen for the Treatment of Uncomplicated Cellulitis in Emergency Department Patients | Completed | Brigham and Women's Hospital | N/A | 2007-05-01 | The primary aim of this study is to quantify the effectiveness of Bactrim as additional therapy for the treatment of uncomplicated cellulitis in adults, by comparing: standard therapy plus Bactrim, versus standard therapy plus placebo. The primary hypothesis of this study is that, in light of increasing CA-MRSA prevalence, subjects treated with standard therapy plus Bactrim will have higher cure rates than those treated with standard therapy plus placebo. |
| NCT00957827 ↗ | Prophylactic Use of Antibiotics for Through and Through Lacerations of the Lip | Terminated | University of Pennsylvania | N/A | 2009-08-01 | Facial lacerations are a commonly encountered problem in the emergency department. Despite this, few original articles have been written concerning the management of lacerations of the lip which communicate with the oral cavity. Specifically, no study has been able to definitively show whether the use of antibiotics for these wounds decreases the infection rate. These cutaneous wounds are a unique type of laceration because they are continuously contaminated with oropharyngeal flora. Contaminated wounds result in larger, less cosmetic scars. Scars which involve the face have been shown to have a negative psychological impact. In this study, the investigators aim to determine whether the use of antibiotics decrease the rate of infection in lacerations of the lip which communicate with the oral cavity. Patients will be randomized to one of two currently practiced therapies. Patients will receive either cephalexin or no treatment following the repair of their through-and-through lip lacerations to determine whether antibiotics decrease the infection rate in these wounds. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for KEFLEX
Condition Name
Clinical Trial Locations for KEFLEX
Trials by Country
Clinical Trial Progress for KEFLEX
Clinical Trial Phase
Clinical Trial Sponsors for KEFLEX
Sponsor Name
