CLINICAL TRIALS PROFILE FOR KOVANAZE
✉ Email this page to a colleague
All Clinical Trials for KOVANAZE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT03368391 ↗ | : Pulpal Blood Flow With the Use of Intra-nasal Anesthetic | Unknown status | Louisiana State University Health Sciences Center in New Orleans | Phase 4 | 2018-01-03 | Anesthetics with vasoconstrictors decrease pulpal blood flow but the impact of intranasal local anesthetics on blood flow is unknown. This blinded, randomized crossover clinical trial will compare the effects of different local anesthetics on anterior teeth in healthy volunteers. On separate study visits patients will receive either traditional injections or intranasal administration of the following solutions: 2% lidocaine with 1:100,000 epi, 3% mepivacaine, tetracaine HCl and oxymetazoline HCl, or saline. The following variables will be assessed: pulpal blood flow, pulpal sensibility, pain on administration, and adverse outcomes. |
| NCT03502135 ↗ | Efficacy of Tetracaine/Oxymetazoline Nasal Spray for Endodontic Treatment | Withdrawn | University of North Carolina, Chapel Hill | Phase 4 | 2018-09-01 | Purpose: To evaluate anesthetic efficacy and overall patient experience with use of Kovanaze tetracaine/oxymetazoline nasal spray for root canal treatment of vital premolar and anterior teeth needing root canal treatment. Participants: 30 adult patients with a vital upper anterior or premolar tooth (#4-13) with a diagnosis indicating need root canal treatment and who are seeking treatment in the UNC Chapel Hill School of Dentistry. Procedures (methods): Qualifying patients will be anesthetized with tetracaine/oxymetazoline nasal spray anesthetic in order to facilitate completion of their clinically required, standard of care root canal treatment. Research procedures include blood pressure monitoring and pain assessment using a visual analogue pain scale. |
| NCT03962634 ↗ | Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Pediatric | Terminated | Virginia Commonwealth University | Phase 2 | 2019-08-28 | The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia. |
| NCT04104789 ↗ | Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - General | Withdrawn | Virginia Commonwealth University | Phase 2 | 2020-09-01 | The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia. |
| NCT04105985 ↗ | Kovanaze Vs. Articaine in Achieving Pulpal Anesthesia of Maxillary Teeth - Endodontics | Withdrawn | Virginia Commonwealth University | Phase 2 | 2020-08-01 | The primary goal of the study is to compare the success rates of pulpal anesthesia (defined as ability to complete the intended dental procedure without the need for rescue anesthesia) between Kovanaze nasal mist and Articaine needle anesthesia. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for KOVANAZE
Condition Name
Clinical Trial Locations for KOVANAZE
Trials by Country
Clinical Trial Progress for KOVANAZE
Clinical Trial Phase
Clinical Trial Sponsors for KOVANAZE
Sponsor Name
