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Last Updated: December 23, 2024

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CLINICAL TRIALS PROFILE FOR KRAZATI

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All Clinical Trials for KRAZATI

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT05840510 ↗	Adagrasib in Combination With Nab-Sirolimus in Patients Wtih Advanced Solid Tumors and Non-Small Cell Lung Cancer Wtih a KRAS G12C Mutation (KRYSTAL -19)	Not yet recruiting	Aadi Bioscience, Inc.	Phase 1/Phase 2	2023-05-31	This study will evaluate the safety, MTD and/or RP2D, PK, and clinical activity of the combination of adagrasib with nab-sirolimus in patients with advanced solid tumors/NSCLC with a KRAS G12C mutation.
NCT05840510 ↗	Adagrasib in Combination With Nab-Sirolimus in Patients Wtih Advanced Solid Tumors and Non-Small Cell Lung Cancer Wtih a KRAS G12C Mutation (KRYSTAL -19)	Not yet recruiting	Mirati Therapeutics Inc.	Phase 1/Phase 2	2023-05-31	This study will evaluate the safety, MTD and/or RP2D, PK, and clinical activity of the combination of adagrasib with nab-sirolimus in patients with advanced solid tumors/NSCLC with a KRAS G12C mutation.
NCT05853575 ↗	Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)	Recruiting	Mirati Therapeutics Inc.	Phase 2	2023-04-05	This study will evaluate the efficacy of two dosing regimens of adagrasib (600 mg BID versus 400 mg BID) in patients with NSCLC with KRAS G12C mutation.
NCT06026410 ↗	KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors	Recruiting	Mirati Therapeutics Inc.	Phase 1	2023-10-18	This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyl transferase inhibitor (FTI), as a monotherapy and in combination, in adult patients with advanced solid tumors.
NCT06026410 ↗	KO-2806 Monotherapy and Combination Therapies in Advanced Solid Tumors	Recruiting	Kura Oncology, Inc.	Phase 1	2023-10-18	This first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyl transferase inhibitor (FTI), as a monotherapy and in combination, in adult patients with advanced solid tumors.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for KRAZATI

Condition Name

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Condition Name for KRAZATI
Intervention	Trials
Advanced Cancer	2
Metastatic Cancer	2
Non Small Cell Lung Cancer (NSCLC)	1
NSCLC	1
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Condition MeSH

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Condition MeSH for KRAZATI
Intervention	Trials
Neoplasms	3
Carcinoma, Renal Cell	1
Neoplasm Metastasis	1
Lung Neoplasms	1
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Clinical Trial Locations for KRAZATI

Trials by Country

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Trials by Country for KRAZATI
Location	Trials
United States	17
Canada	3
Italy	1
United Kingdom	1
Spain	1
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Trials by US State

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Trials by US State for KRAZATI
Location	Trials
California	3
Tennessee	2
Colorado	2
Virginia	1
Texas	1
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Clinical Trial Progress for KRAZATI

Clinical Trial Phase

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Clinical Trial Phase for KRAZATI
Clinical Trial Phase	Trials
Phase 2	1
Phase 1/Phase 2	1
Phase 1	2
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Clinical Trial Status

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Clinical Trial Status for KRAZATI
Clinical Trial Phase	Trials
Recruiting	3
Not yet recruiting	1
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Clinical Trial Sponsors for KRAZATI

Sponsor Name

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Sponsor Name for KRAZATI
Sponsor	Trials
Mirati Therapeutics Inc.	4
Aadi Bioscience, Inc.	1
Kura Oncology, Inc.	1
[disabled in preview]	1
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Sponsor Type

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Sponsor Type for KRAZATI
Sponsor	Trials
Industry	7
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