CLINICAL TRIALS PROFILE FOR LAPATINIB DITOSYLATE
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All Clinical Trials for LAPATINIB DITOSYLATE
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT00085020 ↗ | GW572016 and Trastuzumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2/Neu | Completed | GlaxoSmithKline | Phase 1 | 2004-03-01 | RATIONALE: GW572016 may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Monoclonal antibodies, such as trastuzumab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Giving GW572016 with trastuzumab may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of GW572016 when given together with trastuzumab in treating patients with metastatic breast cancer that overexpresses HER2/neu. |
NCT00085020 ↗ | GW572016 and Trastuzumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2/Neu | Completed | National Cancer Institute (NCI) | Phase 1 | 2004-03-01 | RATIONALE: GW572016 may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Monoclonal antibodies, such as trastuzumab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Giving GW572016 with trastuzumab may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of GW572016 when given together with trastuzumab in treating patients with metastatic breast cancer that overexpresses HER2/neu. |
NCT00085020 ↗ | GW572016 and Trastuzumab in Treating Patients With Metastatic Breast Cancer That Overexpresses HER2/Neu | Completed | Jonsson Comprehensive Cancer Center | Phase 1 | 2004-03-01 | RATIONALE: GW572016 may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Monoclonal antibodies, such as trastuzumab, can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. Giving GW572016 with trastuzumab may kill more tumor cells. PURPOSE: This phase I trial is studying the side effects and best dose of GW572016 when given together with trastuzumab in treating patients with metastatic breast cancer that overexpresses HER2/neu. |
NCT00095563 ↗ | Lapatinib in Treating Patients With Recurrent and/or Metastatic Adenoid Cystic Cancer or Other Salivary Gland Cancers | Completed | National Cancer Institute (NCI) | Phase 2 | 2004-09-01 | Phase II trial to study the effectiveness of lapatinib in treating patients who have recurrent and/or metastatic adenoid cystic cancer or other salivary gland cancers. Lapatinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. |
NCT00095667 ↗ | Lapatinib in Treating Patients With Recurrent or Metastatic Prostate Cancer | Completed | National Cancer Institute (NCI) | Phase 2 | 2004-11-01 | Lapatinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. Phase II trial to study the effectiveness of lapatinib in treating patients who have recurrent or metastatic prostate cancer. |
NCT00095940 ↗ | Lapatinib in Treating Young Patients With Recurrent or Refractory Central Nervous System Tumors | Completed | National Cancer Institute (NCI) | Phase 1/Phase 2 | 2004-10-01 | This phase I/II trial studies lapatinib to see how well it works in treating young patients with recurrent or refractory central nervous system (CNS) tumors. Lapatinib may stop the growth of tumor cells by blocking the enzymes necessary for their growth. |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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