Topical Bupivacaine Effect On The Response To Awake Extubation During Emergence From General Anesthesia
Recruiting
Zagazig University
N/A
2020-07-12
- Emergence from general anesthesia is often complicated by the ETT-induced emergence
phenomena (EP), which include coughing, sympathetic stimulation, sore throat, increased
bleeding from the surgical site, and increased intracranial and intraocular pressures.
- Techniques that have been used to help diminish coughing during emergence include "deep"
extubation (removal of the endotracheal tube [ETT] while the patient is still in a deep
plane of general anesthesia), administration of intravenous (IV) narcotics, or
administration of IV lidocaine prior to emergence since systemic narcotics and lidocaine
have antitussive properties. However, each of these techniques has limitations. A
reliable technique for improving ETT tolerance while facilitating rapid and full
emergence from general anesthesia would be desirable in many situations.
- Topical application of bupivacaine to the pharyngeal, laryngeal, and tracheal mucosa
will attenuate or even abolish coughing as well as a hemodynamic response during
extubation, thus result in increasing the patient's comfort and avoiding potential
complications of extubation process.
- Up to the investigator's knowledge there is no study done to evaluate the effect of
topical bupivacaine on the incidence of coughing and hemodynamic response during
emergence from general anesthesia in patients undergoing elective thyroidectomy.
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