CLINICAL TRIALS PROFILE FOR LONSURF
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All Clinical Trials for LONSURF
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT01896856 ↗ | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | Completed | Astex Pharmaceuticals, Inc. | Phase 1/Phase 2 | 2013-10-23 | This is a phase I/II study of the combination of Guadecitabine (SGI-110) and previously treated metastatic colorectal cancer patients. This study will be conducted in two components. First, patients will be enrolled in a phase I study of SGI-110 combined with irinotecan in a standard 3+3 design. After the maximum tolerated dose (MTD) is determined, patients will subsequently be enrolled in a 2:1 randomized phase II study of SGI-110 and irinotecan versus the standard of care regorafenib or Lonsurf (TAS-102). |
| NCT01896856 ↗ | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | Completed | Van Andel Research Institute | Phase 1/Phase 2 | 2013-10-23 | This is a phase I/II study of the combination of Guadecitabine (SGI-110) and previously treated metastatic colorectal cancer patients. This study will be conducted in two components. First, patients will be enrolled in a phase I study of SGI-110 combined with irinotecan in a standard 3+3 design. After the maximum tolerated dose (MTD) is determined, patients will subsequently be enrolled in a 2:1 randomized phase II study of SGI-110 and irinotecan versus the standard of care regorafenib or Lonsurf (TAS-102). |
| NCT01896856 ↗ | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | Completed | Sidney Kimmel Comprehensive Cancer Center | Phase 1/Phase 2 | 2013-10-23 | This is a phase I/II study of the combination of Guadecitabine (SGI-110) and previously treated metastatic colorectal cancer patients. This study will be conducted in two components. First, patients will be enrolled in a phase I study of SGI-110 combined with irinotecan in a standard 3+3 design. After the maximum tolerated dose (MTD) is determined, patients will subsequently be enrolled in a 2:1 randomized phase II study of SGI-110 and irinotecan versus the standard of care regorafenib or Lonsurf (TAS-102). |
| NCT01896856 ↗ | Phase I/II Study of SGI-110 With Irinotecan Versus Regorafenib or TAS-102 in Metastatic Colorectal Cancer | Completed | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | Phase 1/Phase 2 | 2013-10-23 | This is a phase I/II study of the combination of Guadecitabine (SGI-110) and previously treated metastatic colorectal cancer patients. This study will be conducted in two components. First, patients will be enrolled in a phase I study of SGI-110 combined with irinotecan in a standard 3+3 design. After the maximum tolerated dose (MTD) is determined, patients will subsequently be enrolled in a 2:1 randomized phase II study of SGI-110 and irinotecan versus the standard of care regorafenib or Lonsurf (TAS-102). |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for LONSURF
Condition Name
| Condition Name for LONSURF | |
| Intervention | Trials |
| Stage IV Colorectal Cancer AJCC v8 | 6 |
| Stage IVB Colorectal Cancer AJCC v8 | 6 |
| Stage IVA Colorectal Cancer AJCC v8 | 6 |
| Stage IVC Colorectal Cancer AJCC v8 | 6 |
| [disabled in preview] | 0 |
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Clinical Trial Locations for LONSURF
Trials by Country
Clinical Trial Progress for LONSURF
Clinical Trial Phase
Clinical Trial Sponsors for LONSURF
Sponsor Name
