A multicenter study to evaluate the safety and efficacy of Zylet compared to vehicle in
children aged 0-6 for the management of lid inflammation (chalazion/hordeolum)
The objective of this study is to evaluate the safety and efficacy of Zylet vs. Tobradex in
the treatment of ocular inflammation associated with blepharokeratoconjunctivitis
A Retrospective Evaluation of the Intraocular Pressure Spikes With Loteprednol and Loteprednol/Tobramycin
Completed
Allergan
2009-01-01
Patient charts will be reviewed to evaluate the incidence of intraocular pressure spikes
while on Loteprednol etabonate ophthalmic suspension 0.5%, Loteprednol etabonate (0.5%) and
tobramycin (0.3%)
Concentration of Besifloxacin, Gatifloxacin, and Moxifloxacin in Human Conjunctiva After Topical Instillation
Completed
Bausch & Lomb Incorporated
Phase 1
2009-03-01
The purpose of this study is to assess the concentration of besifloxacin compared to
gatifloxacin and moxifloxacin in human conjunctival tissue, following a single drop of the
drug instilled topically into the study eye. Conjunctival biopsies will be performed at
specified time points, followed by the use of loteprednol etabonate/tobramycin ophthalmic
suspension four times a day for 5 days.
Loteprednol and Tobramycin Versus Tobramycin and Dexamethasone, in the Treatment of Blepharokeratoconjunctivitis
Completed
Bausch & Lomb Incorporated
Phase 3
2009-10-01
This study is to evaluate the safety and efficacy of loteprednol etabonate [LE] and
tobramycin ophthalmic suspension versus tobramycin and dexamethasone ophthalmic suspension in
the treatment of ocular inflammation associated with blepharokeratoconjunctivitis (BKC).
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