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Last Updated: November 25, 2024

CLINICAL TRIALS PROFILE FOR LURBINECTEDIN

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All Clinical Trials for LURBINECTEDIN

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT01314599 ↗	Clinical Study of PM01183 in Patients With Acute Leukemia or Relapsed/Refractory Myelodysplastic Syndrome	Completed	PharmaMar	Phase 1	2011-05-01	Phase I Study of PM01183 in Patients with Advanced Acute Leukemia to determine the maximum tolerated dose (MTD) and the recommended dose (RD) of PM01183.
NCT01831089 ↗	Phase I Study of Lurbinectedin (PM01183) in Combination With Paclitaxel, With or Without Bevacizumab, in Selected Advanced Solid Tumors	Completed	PharmaMar	Phase 1	2013-09-01	Clinical trial of PM01183 in combination with paclitaxel, with or without bevacizumab, in patients with solid tumors
NCT01951157 ↗	A Clinical Study in Three-arm of Lurbinectedin (PM01183) Alone or in Combination With Gemcitabine and a Control Arm With Docetaxel as Second Line Treatment in Non-Small Cell Lung Cancer (NSCLC) Patients	Completed	PharmaMar	Phase 2	2013-09-11	A clinical study of lurbinectedin(PM01183) alone or in combination with gemcitabine in comparison to docetaxel for the treatment of unresectable non-small cell lung cancer (NSCLC)patients
NCT01980667 ↗	Study of Lurbinectedin (PM01183) in Combination With Cisplatin in Patients With Solid Tumors	Completed	PharmaMar	Phase 1	2014-07-30	Clinical and Pharmacokinetic Study of Lurbinectedin (PM01183) in Combination with Cisplatin in Patients with Advanced Solid Tumors to determine the recommended dose (RD) of PM01183 in combination with cisplatin, to characterize the safety profile, the pharmacokinetics (PK) of this combination, to obtain preliminary information on the clinical antitumor activity and to conduct an exploratory pharmacogenomic (PGx) analysis.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for LURBINECTEDIN

Condition Name

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Condition Name for LURBINECTEDIN
Intervention	Trials
Advanced Solid Tumor	5
Small-cell Lung Cancer	5
Ovarian Cancer	4
Advanced Solid Tumors	3
[disabled in preview]	0
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Condition MeSH

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Condition MeSH for LURBINECTEDIN
Intervention	Trials
Lung Neoplasms	12
Small Cell Lung Carcinoma	11
Neoplasms	7
Sarcoma	6
[disabled in preview]	0
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Clinical Trial Locations for LURBINECTEDIN

Trials by Country

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Trials by Country for LURBINECTEDIN
Location	Trials
United States	90
Spain	24
Italy	12
United Kingdom	7
France	7
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Trials by US State

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Trials by US State for LURBINECTEDIN
Location	Trials
Massachusetts	9
Texas	8
California	7
Pennsylvania	6
New York	5
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Clinical Trial Progress for LURBINECTEDIN

Clinical Trial Phase

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Clinical Trial Phase for LURBINECTEDIN
Clinical Trial Phase	Trials
Phase 3	5
Phase 2/Phase 3	1
Phase 2	11
[disabled in preview]	9
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Clinical Trial Status

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Clinical Trial Status for LURBINECTEDIN
Clinical Trial Phase	Trials
Not yet recruiting	15
Completed	10
Recruiting	9
[disabled in preview]	1
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Clinical Trial Sponsors for LURBINECTEDIN

Sponsor Name

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Sponsor Name for LURBINECTEDIN
Sponsor	Trials
PharmaMar	19
Jazz Pharmaceuticals	9
National Cancer Institute (NCI)	3
[disabled in preview]	2
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Sponsor Type

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Sponsor Type for LURBINECTEDIN
Sponsor	Trials
Industry	36
Other	19
NIH	3
[disabled in preview]	0
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