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Last Updated: March 28, 2025

CLINICAL TRIALS PROFILE FOR MAGNESIUM SULFATE


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All Clinical Trials for MAGNESIUM SULFATE

Trial IDTitleStatusSponsorPhaseStart DateSummary
NCT00004399 ↗ Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia Completed University of Utah N/A 1995-09-01 OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
NCT00004399 ↗ Randomized Study of Nimodipine Versus Magnesium Sulfate in the Prevention of Eclamptic Seizures in Patients With Severe Preeclampsia Completed FDA Office of Orphan Products Development N/A 1995-09-01 OBJECTIVES: I. Determine the effectiveness of nimodipine versus magnesium sulfate in the prevention of eclamptic seizures in patients with severe preeclampsia.
NCT00002146 ↗ Safety and Efficacy of Intravenous Magnesium Sulfate in Modulating Changes in Symptoms and Divalent Cation Levels Associated With Foscavir Therapy: A Phase IV Randomized, Double-Blind, Placebo-Controlled, Cross-Over, Pilot Study Completed Astra USA Phase 4 1969-12-31 To determine whether acute ionized hypomagnesemia and hypocalcemia immediately following foscarnet infusions can be lessened or eliminated by prior infusion of magnesium sulfate. To determine whether reductions in ionized magnesium, ionized calcium, and parathyroid hormone levels following foscarnet infusions are lessened by preinfusion of magnesium sulfate. To evaluate the safety of intravenous magnesium sulfate prior to foscarnet infusion by monitoring blood pressure, heart rate, and heart rhythm. To characterize the effect of magnesium sulfate on foscarnet blood levels and urinary excretion of calcium, magnesium, phosphate, and foscarnet.
>Trial ID>Title>Status>Phase>Start Date>Summary
Showing 1 to 3 of 3 entries

Clinical Trial Conditions for MAGNESIUM SULFATE

Condition Name

2111110-20246810121416182022Postoperative PainPreeclampsiaMagnesium Sulfate[disabled in preview]
Condition Name for MAGNESIUM SULFATE
Intervention Trials
Postoperative Pain 21
Preeclampsia 11
Magnesium Sulfate 11
[disabled in preview] 0
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Condition MeSH

37261700510152025303540Pain, PostoperativePre-EclampsiaObstetric Labor, Premature[disabled in preview]
Condition MeSH for MAGNESIUM SULFATE
Intervention Trials
Pain, Postoperative 37
Pre-Eclampsia 26
Obstetric Labor, Premature 17
[disabled in preview] 0
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Clinical Trial Locations for MAGNESIUM SULFATE

Trials by Country

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Trials by Country for MAGNESIUM SULFATE
Location Trials
United States 130
Egypt 84
Korea, Republic of 18
Brazil 17
Canada 12
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Trials by US State

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Trials by US State for MAGNESIUM SULFATE
Location Trials
California 13
Ohio 9
New York 9
Pennsylvania 8
Illinois 7
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Clinical Trial Progress for MAGNESIUM SULFATE

Clinical Trial Phase

55.4%29.1%15.5%00102030405060708090Phase 4Phase 3Phase 2/Phase 3[disabled in preview]
Clinical Trial Phase for MAGNESIUM SULFATE
Clinical Trial Phase Trials
Phase 4 82
Phase 3 43
Phase 2/Phase 3 23
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Clinical Trial Status

58.3%22.8%18.9%0020406080100120140160CompletedRecruitingNot yet recruiting[disabled in preview]
Clinical Trial Status for MAGNESIUM SULFATE
Clinical Trial Phase Trials
Completed 148
Recruiting 58
Not yet recruiting 48
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Clinical Trial Sponsors for MAGNESIUM SULFATE

Sponsor Name

trials05101520253035Assiut UniversityCairo UniversitySeoul National University Bundang Hospital[disabled in preview]
Sponsor Name for MAGNESIUM SULFATE
Sponsor Trials
Assiut University 33
Cairo University 17
Seoul National University Bundang Hospital 13
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Sponsor Type

94.0%0050100150200250300350400OtherNIHIndustry[disabled in preview]
Sponsor Type for MAGNESIUM SULFATE
Sponsor Trials
Other 394
NIH 13
Industry 12
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Magnesium Sulfate: Clinical Trials, Market Analysis, and Projections

Introduction to Magnesium Sulfate

Magnesium sulfate, commonly known as Epsom salt, is a versatile compound with a wide range of applications in agriculture, healthcare, and various industries. This article delves into the current clinical trials, market analysis, and future projections for magnesium sulfate.

Clinical Trials: Magnesium Sulfate as an Adjunctive Analgesic

Purpose and Design

An ongoing clinical trial is investigating the efficacy of magnesium sulfate as an adjunctive analgesic in prostate surgery. The primary objective is to determine if magnesium sulfate can reduce pain scores in patients undergoing prostate surgery. The trial involves randomizing patients to receive either magnesium sulfate or a placebo as part of a standardized general anesthetic[1][4].

Key Objectives

  • Primary Objective: To demonstrate improved pain scores in patients receiving magnesium sulfate.
  • Secondary Objectives: To reduce the requirements for other opioids, minimize postoperative shivering, improve discharge home times, and ensure adequate neuromuscular blockade reversal.

Participant Criteria

  • Inclusion Criteria: Patients aged 18 and older undergoing robotic prostatectomy under general anesthesia.
  • Exclusion Criteria: Patients younger than 18, those with end-stage renal disease, known allergy to magnesium sulfate, and any patient unable to comply with study procedures[1][4].

Market Analysis: Current Trends and Drivers

Global Market Size and Growth

The global magnesium sulfate market is substantial and growing. In 2023, the market size was approximately USD 1 billion and is projected to reach USD 1.58 billion by 2032, growing at a CAGR of 5.5%[3].

Key Drivers

  • Agricultural Use: Magnesium sulfate is crucial in agriculture for correcting soil deficiencies in magnesium and sulfur, enhancing crop nutrition and yield. This application drives over 50% of the demand[5].
  • Pharmaceutical Applications: The compound is used in various pharmaceutical products, including IV solutions, laxatives, and treatments for conditions like eclampsia and preeclampsia[3].
  • Personal Care: Increasing demand for cosmetic products, particularly among the female population, is also driving the market[3].

Regional Analysis

  • Asia Pacific: This region dominates the global market with a significant share, driven by rapid industrialization and the expanding agricultural sectors in countries like China and India. China is expected to grow at a CAGR of 4.1% until 2033[2][5].
  • North America: This region follows closely, with the U.S. and Canada being key markets due to the widespread use of magnesium sulfate in healthcare and agriculture[5].

Market Projections: Future Growth and Opportunities

Short-Term Growth (2023-2026)

The market is expected to experience rapid growth during this period, driven by the rising utilization of magnesium sulfate in chemicals, agriculture, pharmaceuticals, and other end-use industries. The integration of magnesium sulfate with other agricultural fertilizers and its use in medication against constipation are key factors[2].

Mid-Term Growth (2026-2029)

Growth in this period is likely to be attributed to the expanding agricultural sector and significant developments in end-use industries. The demand from the food and beverage industry is also expected to augment market growth[2].

Long-Term Projections (2029-2033)

The global magnesium sulfate market is forecasted to continue growing at a CAGR of 5.1% to 5.7% until 2033. The market is expected to reach USD 1.485 billion by 2033, driven by sustained demand in agriculture, healthcare, and personal care sectors[2][3][5].

Challenges and Restraints

Despite the positive growth projections, the market faces several challenges:

  • Price Volatility: Fluctuations in the prices of magnesium salts due to rising energy and raw material costs can impact market growth[3].
  • Health Concerns: Adverse effects of magnesium compound-based drugs, such as hives, diarrhea, and difficulty in breathing, can hinder demand[3].
  • Raw Material Availability: Reduction in the availability of high-quality minerals can influence the prices and availability of magnesium sulfate[3].

Key Takeaways

  • Global Market Growth: The magnesium sulfate market is projected to grow from USD 1 billion in 2023 to USD 1.58 billion by 2032 at a CAGR of 5.5%.
  • Agricultural Dominance: Agriculture drives over 50% of the demand for magnesium sulfate due to its effectiveness in improving soil health and crop yields.
  • Regional Leadership: Asia Pacific, particularly China and India, leads the global market, followed by North America.
  • Pharmaceutical and Personal Care: Increasing demand in pharmaceutical and personal care applications is a significant driver of market growth.

FAQs

What is the primary objective of the clinical trial involving magnesium sulfate in prostate surgery?

The primary objective is to determine if receiving magnesium sulfate as an adjunctive analgesic can reduce pain scores in patients undergoing prostate surgery[1][4].

What are the key drivers of the magnesium sulfate market?

The key drivers include agricultural use, pharmaceutical applications, and increasing demand in personal care products[3][5].

Which region dominates the global magnesium sulfate market?

Asia Pacific, particularly China and India, dominates the global market due to rapid industrialization and the expanding agricultural sectors[2][5].

What are the challenges facing the magnesium sulfate market?

Challenges include price volatility, health concerns related to magnesium compound-based drugs, and the reduction in availability of high-quality minerals[3].

What is the projected market size of magnesium sulfate by 2033?

The global magnesium sulfate market is expected to reach USD 1.485 billion by 2033, growing at a CAGR of 5.1% to 5.7%[2][3][5].

Sources

  1. ClinicalTrials.gov: Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery.
  2. Future Market Insights: Magnesium Sulfate Market - Growth Drivers & Opportunities.
  3. Fortune Business Insights: Magnesium Sulfate Market Size, Share & Growth | Report [2032].
  4. CenterWatch: Magnesium Sulfate as an Adjunctive Analgesic in Prostate Surgery.
  5. Market.US: Magnesium Sulfate Market Size, Share | CAGR of 5.1%.

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