Temozolomide in Patients With Progressive or Recurrent Non-small Cell Lung Cancer
Completed
European Organisation for Research and Treatment of Cancer - EORTC
Phase 2
1997-07-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die.
PURPOSE: Phase II trial to study the effect of temozolomide in patients with progressive or
recurrent stage IV non-small cell lung cancer, with or without brain metastases, who have not
been treated for metastatic disease with chemotherapy.
Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders
Completed
Johns Hopkins University
Phase 2
1985-01-01
OBJECTIVES:
I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium
phenylacetate, and dietary intervention in patients with urea cycle disorders.
Phase II Study of Sodium Phenylbutyrate, Sodium Benzoate, Sodium Phenylacetate, and Dietary Intervention for Urea Cycle Disorders
Completed
National Center for Research Resources (NCRR)
Phase 2
1985-01-01
OBJECTIVES:
I. Assess the safety and efficacy of sodium phenylbutyrate, sodium benzoate, sodium
phenylacetate, and dietary intervention in patients with urea cycle disorders.
Effects of Tumor Necrosis Factor (TNF)-Alpha Antagonism in Patients With Metabolic Syndrome
Completed
Massachusetts General Hospital
Phase 2/Phase 3
2004-04-01
Metabolic syndrome is associated with increased inflammatory cytokines and reduced
adiponectin, that may be mediated in part by TNF production from abdominal fat. We reasoned
that an anti-TNF agent would reduce C-reactive protein (CRP) and increase adiponectin,
improving the inflammatory milieu associated with metabolic syndrome.
Drugs may be covered by multiple patents or regulatory protections. All trademarks and applicant names are the property of their respective owners or licensors.
Although great care is taken in the proper and correct provision of this service, thinkBiotech LLC does not accept any responsibility for possible consequences of errors or omissions in the provided data.
The data presented herein is for information purposes only. There is no warranty that the data contained herein is error free.
thinkBiotech performs no independent verification of facts as provided by public sources nor are attempts made to provide legal or investing advice. Any reliance on data provided herein is done solely at the discretion of the user.
Users of this service are advised to seek professional advice and independent confirmation before considering acting on any of the provided information. thinkBiotech LLC reserves the right to amend, extend or withdraw any part or all of the offered service without notice.
Alerts Available With Subscription
Alerts are available for users with active subscriptions.
