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Last Updated: November 5, 2024

CLINICAL TRIALS PROFILE FOR MEDROL ACETATE


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All Clinical Trials for MEDROL ACETATE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT04515966 ↗ A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome Recruiting Mercy Health Ohio Phase 4 2020-12-01 Carpal Tunnel Syndrome (CTS) is caused by compression of a nerve called the median nerve as it travels through a narrow tunnel within the wrist on its way to the hand. Compression of the median nerve causes numbness, tingling, pain and weakness of the hand and fingers. CTS is usually treated with rest or a change in the activity level. It can also be treated with a splint that limits bending of the hand and wrist. Other treatments include a steroid injection near the median nerve. Surgery can be performed if the symptoms are severe or persistent. Compression of the median nerve can cause swelling that may be observed with ultrasound of the wrist. Ultrasound can also be used to help guide the needle to inject the steroid solution in close proximity to the median nerve while avoiding injury to the nerve. The investigators plan to compare the effectiveness of a splint and an ultrasound-guided steroid injection in the treatment of mild to moderate CTS. Individuals with CTS who agree to participate, will be randomly assigned to two groups. One group will be treated with a splint and the other with a steroid injection performed under ultrasound guidance. The severity of CTS symptoms will be determined prior to beginning the study and also at 6 weeks, 3 months, 6 months and 1 year following each of the two treatment interventions. The median nerve size (diameter) will be measured in all participants prior to beginning the study and also following both treatment interventions at 6 weeks, 3 months, 6 months and 1 year. At the conclusion of the study, the investigators will determine which of the two treatments, splint or steroid injection, is more effective in alleviating CTS symptoms. The investigators will also determine if either or both treatments result in a change in swelling of the median nerve as measured by ultrasound.
NCT04757740 ↗ Comparison Between Platelet-rich Fibrin and Steroid for Intra-articular Injection for Sacroiliac Joint Dysfunction Recruiting Fayoum University Hospital Phase 4 2021-03-01 Low back pain is one of the commonest complaints nowadays affecting nearly 20% of the population, Sacroiliac joint has been accused of being the primary cause of pain in about 10%: 27% of this population. The sure diagnosis of sacroiliac joint pain is challenging because of multiple crossed factors of facet joint pain and intervertebral disc pain. Diagnosis can be done by history taking, local examination, imaging techniques, and controlled local anesthetic blocks. Controlled local anesthetic blocks are diagnostic and therapeutic done by various methods either landmark-guided or imaging-assisted either by fluoroscopy, computed tomography (CT), magnetic resonance (MRI), or ultrasound-guided. Lower cost, real-time viewing of needle leading to higher accuracy rate, and low ionizing radiation dose are favoring ultrasound-guided injection over other modalities. Numerous treatment modalities are being used for sacroiliac joint pain ranging from physiotherapy and systemic analgesics like Non-steroidal anti-inflammatory drugs (NSAIDs) to minimally invasive intra-articular, periarticular injection, radiofrequency neurotomy, and surgical fusion of the joint. Multiple injectates are being used for intraarticular injection most commonly local anesthetics and steroids which offer short-term symptomatic relief and delay the degenerative process. The need for a longer duration effect directly affects the disease process itself aiming for accelerating the joint healing rate by biological growth factors found in human blood especially in platelets. Platelet-rich plasma (PRP) has been used aiming to inject a high concentration of growth factors directly into the joint. Platelet-rich fibrin (PRF), the second generation of platelet-rich plasma is now tried having the advantage of a simpler preparation and higher values of growth factors.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for MEDROL ACETATE

Condition Name

Condition Name for MEDROL ACETATE
Intervention Trials
Carpal Tunnel Syndrome 1
Low Back Pain 1
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Condition MeSH

Condition MeSH for MEDROL ACETATE
Intervention Trials
Low Back Pain 1
Joint Diseases 1
Syndrome 1
Carpal Tunnel Syndrome 1
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Clinical Trial Locations for MEDROL ACETATE

Trials by Country

Trials by Country for MEDROL ACETATE
Location Trials
Egypt 1
United States 1
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Trials by US State

Trials by US State for MEDROL ACETATE
Location Trials
Ohio 1
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Clinical Trial Progress for MEDROL ACETATE

Clinical Trial Phase

Clinical Trial Phase for MEDROL ACETATE
Clinical Trial Phase Trials
Phase 4 2
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Clinical Trial Status

Clinical Trial Status for MEDROL ACETATE
Clinical Trial Phase Trials
Recruiting 2
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Clinical Trial Sponsors for MEDROL ACETATE

Sponsor Name

Sponsor Name for MEDROL ACETATE
Sponsor Trials
Mercy Health Ohio 1
Fayoum University Hospital 1
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Sponsor Type

Sponsor Type for MEDROL ACETATE
Sponsor Trials
Other 2
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