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Last Updated: March 24, 2025

CLINICAL TRIALS PROFILE FOR MEFOXIN IN PLASTIC CONTAINER


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All Clinical Trials for MEFOXIN IN PLASTIC CONTAINER

Trial IDTitleStatusSponsorPhaseStart DateSummary
NCT00343317 ↗ Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women Completed Bristol-Myers Squibb N/A 2003-02-01 Postpartum infections are among the leading causes of maternal mortality world-wide, particularly in under-resourced countries. Available data suggests that HIV infected women are at greater risk of postpartum complications than uninfected women. In South Africa, HIV/AIDS and related infections are now cumulatively the leading causes of maternal deaths (though indirectly), with puerperal sepsis among the 5 most common causes. This was a prospective longitudinal cohort of HIV infected (n = 675) and uninfected (n = 648) women. These were women in whom vaginal delivery was anticipated, and were recruited at > 36 weeks of gestation during the antenatal period. Hypothesis - HIV infected women are at increased risk of postpartum infectious morbidity and this morbidity can be reduced by use of prophylactic intrapartum antibiotics.
NCT00343317 ↗ Prophylactic Intrapartum Antibiotics and Immunological Markers for Postpartum Morbidity in HIV Positive Women Completed University of KwaZulu N/A 2003-02-01 Postpartum infections are among the leading causes of maternal mortality world-wide, particularly in under-resourced countries. Available data suggests that HIV infected women are at greater risk of postpartum complications than uninfected women. In South Africa, HIV/AIDS and related infections are now cumulatively the leading causes of maternal deaths (though indirectly), with puerperal sepsis among the 5 most common causes. This was a prospective longitudinal cohort of HIV infected (n = 675) and uninfected (n = 648) women. These were women in whom vaginal delivery was anticipated, and were recruited at > 36 weeks of gestation during the antenatal period. Hypothesis - HIV infected women are at increased risk of postpartum infectious morbidity and this morbidity can be reduced by use of prophylactic intrapartum antibiotics.
>Trial ID>Title>Status>Phase>Start Date>Summary
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Clinical Trial Conditions for MEFOXIN IN PLASTIC CONTAINER

Condition Name

10-0.100.10.20.30.40.50.60.70.80.911.1Puerperal Sepsis[disabled in preview]
Condition Name for MEFOXIN IN PLASTIC CONTAINER
Intervention Trials
Puerperal Sepsis 1
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Condition MeSH

110-0.100.10.20.30.40.50.60.70.80.911.1SepsisHIV Seropositivity[disabled in preview]
Condition MeSH for MEFOXIN IN PLASTIC CONTAINER
Intervention Trials
Sepsis 1
HIV Seropositivity 1
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Clinical Trial Locations for MEFOXIN IN PLASTIC CONTAINER

Trials by Country

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Trials by Country for MEFOXIN IN PLASTIC CONTAINER
Location Trials
South Africa 1
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Clinical Trial Progress for MEFOXIN IN PLASTIC CONTAINER

Clinical Trial Phase

100.0%0-0.100.10.20.30.40.50.60.70.80.911.1N/A[disabled in preview]
Clinical Trial Phase for MEFOXIN IN PLASTIC CONTAINER
Clinical Trial Phase Trials
N/A 1
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Clinical Trial Status

100.0%0-0.100.10.20.30.40.50.60.70.80.911.1Completed[disabled in preview]
Clinical Trial Status for MEFOXIN IN PLASTIC CONTAINER
Clinical Trial Phase Trials
Completed 1
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Clinical Trial Sponsors for MEFOXIN IN PLASTIC CONTAINER

Sponsor Name

trials000001111111University of KwaZuluBristol-Myers Squibb[disabled in preview]
Sponsor Name for MEFOXIN IN PLASTIC CONTAINER
Sponsor Trials
University of KwaZulu 1
Bristol-Myers Squibb 1
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Sponsor Type

50.0%50.0%0-0.100.10.20.30.40.50.60.70.80.911.1OtherIndustry[disabled in preview]
Sponsor Type for MEFOXIN IN PLASTIC CONTAINER
Sponsor Trials
Other 1
Industry 1
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Mefoxin in Plastic Containers: Clinical Trials, Market Analysis, and Projections

Introduction

Mefoxin, a broad-spectrum cephalosporin antibiotic, has been a crucial component in the treatment of various bacterial infections. Its efficacy against a wide range of gram-positive and some gram-negative bacteria makes it a preferred choice in several medical fields. Here, we will delve into the current state of clinical trials, market analysis, and future projections for Mefoxin, particularly focusing on its formulation in plastic containers.

Clinical Trials and Efficacy

Historical Context

Mefoxin has been extensively studied and used for treating infections caused by susceptible bacteria. Early clinical trials demonstrated its effectiveness, particularly in surgical prophylaxis and the treatment of serious infections. For instance, studies have shown that Mefoxin is highly effective against anaerobic bacteria, making it a preferred choice in colorectal surgeries where the risk of infection is significant[4].

Current Trials

While there are no specific recent clinical trials focused solely on Mefoxin in plastic containers, ongoing research in the broader antibiotic market is relevant. For example, trials on other cephalosporins and antibiotics highlight the continuous need for effective and safe treatments against bacterial infections. The development of new formulations, such as extended-release versions, is enhancing therapeutic efficacy and patient compliance[2].

Safety and Efficacy

Clinical trials have consistently shown that Mefoxin is safe and effective. A study involving 143 patients treated with intravenous cefoxitin (a related cephamycin antibiotic) showed a cure or improvement rate of 93%, with the infecting organism eradicated in all bacteremic patients. The incidence of adverse experiences was relatively low, with no permanent or serious adverse reactions encountered[4].

Market Analysis

Market Drivers

The Mefoxin market is driven by several key factors:

  • Increasing Prevalence of Bacterial Infections: The rising incidence of infectious diseases globally is a significant driver for the demand of effective antibiotics like Mefoxin[2].
  • Antibiotic Resistance: The growing concern of antibiotic resistance has led to increased investment in research and development of new and effective antibiotics, including Mefoxin[2][3].
  • Technological Advancements: Innovations in drug formulations and delivery mechanisms, such as extended-release formulations, are enhancing the therapeutic efficacy of Mefoxin and improving patient compliance[2].

Geographical Trends

The Mefoxin market exhibits varied growth patterns across different regions:

  • Emerging Markets: Countries in Asia-Pacific and Latin America are experiencing a surge in demand for Mefoxin due to increasing healthcare access and a rising burden of infectious diseases[2].
  • Developed Regions: In developed regions, the market is more stable, characterized by stringent regulations and a shift towards more personalized medicine approaches[2].

Competitive Landscape

The competitive landscape of the Mefoxin market is marked by the presence of several key players focused on innovation and strategic collaborations. Companies are investing in research and development to enhance the efficacy of Mefoxin and address the challenge of antibiotic resistance. Partnerships between pharmaceutical companies and healthcare institutions are fostering the development of new treatment protocols[2].

Market Projections

Future Growth

The Mefoxin market is poised for significant growth driven by evolving healthcare needs and advancements in pharmaceutical technology. Here are some key projections:

  • Increasing Demand: With the rising prevalence of bacterial infections and antibiotic resistance, the demand for effective cephalosporins like Mefoxin is expected to rise. By 2050, antibiotic resistance is projected to cause 10 million deaths annually, underscoring the urgency for innovative solutions[2].
  • Personalized Medicine: As healthcare systems increasingly focus on personalized medicine, the ability to tailor antibiotic therapies to individual patient profiles will become paramount. Mefoxin’s pharmacokinetic properties allow for flexible dosing regimens, which will drive demand[2].
  • Geographical Expansion: Emerging markets in Asia and Africa are witnessing a surge in healthcare investments, leading to increased access to essential medicines. This trend is expected to continue, expanding Mefoxin’s market share in these regions[2].

Technological Advancements

The integration of digital health technologies, including telemedicine and mobile health applications, is transforming how antibiotics are prescribed and monitored. This shift offers new avenues for healthcare providers to prescribe Mefoxin more efficiently, ensuring timely treatment for patients[2].

Innovative Applications

Surgical Prophylaxis

Mefoxin’s effectiveness against anaerobic bacteria makes it a preferred choice in surgical prophylaxis, particularly in colorectal surgeries where the risk of infection is significant. Its ability to reduce postoperative complications has positioned Mefoxin as a critical player in enhancing patient outcomes[2].

Combination Therapies

The development of combination therapies, where Mefoxin is used alongside other antibiotics, can enhance treatment outcomes and mitigate resistance. This approach is expected to further solidify Mefoxin’s market position in the fight against bacterial infections[2].

Challenges and Opportunities

Antibiotic Resistance

One of the significant challenges facing the Mefoxin market is the growing issue of antibiotic resistance. However, this also presents an opportunity for Mefoxin, which is known for its efficacy against a broad spectrum of bacteria, including strains resistant to other antibiotics[2][3].

Regulatory Environment

Stringent regulations in developed regions can pose challenges but also drive innovation. Companies must navigate these regulatory environments while focusing on ensuring the safe and effective use of Mefoxin[2].

Key Takeaways

  • Clinical Efficacy: Mefoxin has been consistently shown to be safe and effective in treating bacterial infections.
  • Market Growth: The Mefoxin market is driven by the increasing prevalence of bacterial infections, technological advancements, and geographical expansion.
  • Future Projections: The market is poised for significant growth, with a focus on personalized medicine, combination therapies, and digital health technologies.
  • Challenges and Opportunities: The challenge of antibiotic resistance presents both a risk and an opportunity for Mefoxin to remain a critical component in the fight against bacterial infections.

FAQs

What are the primary drivers of the Mefoxin market?

The primary drivers include the increasing prevalence of bacterial infections, the growing concern of antibiotic resistance, and technological advancements in drug formulations and delivery mechanisms[2].

How does Mefoxin perform in surgical prophylaxis?

Mefoxin is highly effective in surgical prophylaxis, particularly in colorectal surgeries, due to its efficacy against anaerobic bacteria. It significantly reduces postoperative complications and enhances patient outcomes[2].

What are the future projections for the Mefoxin market?

The market is expected to grow significantly, driven by the need for effective antibiotics, the focus on personalized medicine, and the integration of digital health technologies. Emerging markets in Asia and Africa will also contribute to this growth[2].

How does Mefoxin address the issue of antibiotic resistance?

Mefoxin is effective against a broad spectrum of bacteria, including strains resistant to other antibiotics. This makes it a valuable option in the fight against antibiotic resistance, although continuous innovation and combination therapies are necessary to mitigate this issue[2][3].

What role do digital health technologies play in the Mefoxin market?

Digital health technologies, such as telemedicine and mobile health applications, are transforming how antibiotics are prescribed and monitored. This shift offers new avenues for healthcare providers to prescribe Mefoxin more efficiently, ensuring timely treatment for patients[2].

Sources

  1. Mefoxin Market - PW Consulting. Retrieved from https://pmarketresearch.com/hc/mefoxin-market/
  2. Global Mefoxin Market: Things to Focus on to Ensure Long-term. Retrieved from https://www.openpr.com/news/2231427/global-mefoxin-market-things-to-focus-on-to-ensure-long-term
  3. The Continuing Threat of Methicillin-Resistant Staphylococcus aureus. Retrieved from https://www.mdpi.com/2079-6382/8/2/52
  4. Results of a clinical trial of cefoxitin, a new cephamycin antibiotic. Retrieved from https://pubmed.ncbi.nlm.nih.gov/335968/

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