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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR MEROPENEM


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All Clinical Trials for MEROPENEM

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00050401 ↗ Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support Completed AstraZeneca Phase 3 2002-07-01 The purpose of the study is to find out if high dose antibiotic (meropenem, MERREMĀ® I.V.), along with another drug called an aminoglycoside (a different type of antibiotic) is effective in decreasing or reducing the rate of antibiotic resistant Pseudomonas aeruginosa, Acinetobacter (germs that can cause pneumonia), and the rate of resistance in other difficult to treat germs which may cause hospital-acquired pneumonia requiring mechanical ventilatory support. The study hopes to show that by increasing the amount of meropenem administered and increasing the duration of infusion (release of the drug into the bloodstream), levels of the drug will stay at target levels in the bloodstream and decrease the ability of difficult to treat germs to resist, or not be killed by, the treatment using this antibiotic (meropenem) or other antibiotics.
NCT00050401 ↗ Ventilator-Associated Pneumonia/Hospital-Acquired Pneumonia Requiring Mechanical Ventilatory Support Completed Pfizer Phase 3 2002-07-01 The purpose of the study is to find out if high dose antibiotic (meropenem, MERREMĀ® I.V.), along with another drug called an aminoglycoside (a different type of antibiotic) is effective in decreasing or reducing the rate of antibiotic resistant Pseudomonas aeruginosa, Acinetobacter (germs that can cause pneumonia), and the rate of resistance in other difficult to treat germs which may cause hospital-acquired pneumonia requiring mechanical ventilatory support. The study hopes to show that by increasing the amount of meropenem administered and increasing the duration of infusion (release of the drug into the bloodstream), levels of the drug will stay at target levels in the bloodstream and decrease the ability of difficult to treat germs to resist, or not be killed by, the treatment using this antibiotic (meropenem) or other antibiotics.
NCT00061438 ↗ A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed AstraZeneca Phase 4 2003-02-01 This is a research study in patients having a condition known as necrotizing pancreatitis. This is inflammation of the pancreas (an intestinal organ which assists with digestion) that has resulted in the damage and death of some pancreatic tissue. This damaged pancreatic tissue may develop a bacterial infection, which can cause further -sometimes very serious- health problems. It may be possible to prevent or delay infection by giving 'prophylactic' antibiotics (that is - to provide protection before any infection starts). However, it is not certain that this antibiotic therapy will be successful. This study is being carried out to see whether the antibiotic 'Meropenem' (which is also known as MERREM I.V.) provides protection from developing a pancreatic infection. This will be done by comparing the progress of patients who receive meropenem with those who receive a non-active placebo solution (a solution that does not contain any active medication). Meropenem or placebo would be given in addition to the standard treatment received for pancreatitis. It is not known if meropenem will help prevent infections associated with necrotizing pancreatitis. Approximately 240 patients will take part in this study. Study participation will be carried out for up to 6 weeks, and patients will receive the study treatment up to a maximum of 21 days.
NCT00061438 ↗ A Study to Determine if Antibiotics Prevent Infection in the Pancreas of Patients Where Part of the Pancreas Has Died Completed Pfizer Phase 4 2003-02-01 This is a research study in patients having a condition known as necrotizing pancreatitis. This is inflammation of the pancreas (an intestinal organ which assists with digestion) that has resulted in the damage and death of some pancreatic tissue. This damaged pancreatic tissue may develop a bacterial infection, which can cause further -sometimes very serious- health problems. It may be possible to prevent or delay infection by giving 'prophylactic' antibiotics (that is - to provide protection before any infection starts). However, it is not certain that this antibiotic therapy will be successful. This study is being carried out to see whether the antibiotic 'Meropenem' (which is also known as MERREM I.V.) provides protection from developing a pancreatic infection. This will be done by comparing the progress of patients who receive meropenem with those who receive a non-active placebo solution (a solution that does not contain any active medication). Meropenem or placebo would be given in addition to the standard treatment received for pancreatitis. It is not known if meropenem will help prevent infections associated with necrotizing pancreatitis. Approximately 240 patients will take part in this study. Study participation will be carried out for up to 6 weeks, and patients will receive the study treatment up to a maximum of 21 days.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for MEROPENEM

Condition Name

Condition Name for MEROPENEM
Intervention Trials
Sepsis 11
Septic Shock 8
Acute Pyelonephritis 8
Complicated Intra-Abdominal Infection 6
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Condition MeSH

Condition MeSH for MEROPENEM
Intervention Trials
Infections 48
Infection 40
Communicable Diseases 39
Sepsis 23
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Clinical Trial Locations for MEROPENEM

Trials by Country

Trials by Country for MEROPENEM
Location Trials
United States 215
China 54
Spain 47
Italy 29
India 26
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Trials by US State

Trials by US State for MEROPENEM
Location Trials
California 19
Ohio 18
Florida 16
New York 15
Illinois 12
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Clinical Trial Progress for MEROPENEM

Clinical Trial Phase

Clinical Trial Phase for MEROPENEM
Clinical Trial Phase Trials
Phase 4 36
Phase 3 40
Phase 2/Phase 3 5
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Clinical Trial Status

Clinical Trial Status for MEROPENEM
Clinical Trial Phase Trials
Completed 66
Not yet recruiting 22
Recruiting 19
[disabled in preview] 13
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Clinical Trial Sponsors for MEROPENEM

Sponsor Name

Sponsor Name for MEROPENEM
Sponsor Trials
Pfizer 12
AstraZeneca 10
Merck Sharp & Dohme Corp. 8
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Sponsor Type

Sponsor Type for MEROPENEM
Sponsor Trials
Other 161
Industry 79
U.S. Fed 8
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