CLINICAL TRIALS PROFILE FOR MESTINON

All Clinical Trials for MESTINON

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00075101 ↗	Sleep, Fatigue, and Dexamethosone in Children With Leukemia	Completed	National Institute of Nursing Research (NINR)	Phase 3	2000-09-01	The purpose of this study is to determine the relationship between dexamethosone (steroid) and children's sleep and fatigue.
NCT00223691 ↗	Treatment of Orthostatic Hypotension in Autonomic Failure	Completed	Vanderbilt University	Phase 1	2002-03-01	The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.
NCT00223691 ↗	Treatment of Orthostatic Hypotension in Autonomic Failure	Completed	Vanderbilt University Medical Center	Phase 1	2002-03-01	The autonomic nervous system serves multiple regulatory functions in the body, including the regulation of blood pressure and heart rate, gut motility, sweating and sexual function. There are several diseases characterized by abnormal function of the autonomic nervous system. Medications can also alter autonomic function. Impairment of the autonomic nervous system by diseases or drugs may lead to several symptoms, including blood pressure problems (e.g., high blood pressure lying down and low blood pressure on standing), sweating abnormalities, constipation or diarrhea and sexual dysfunction. Because treatment options for these patients are limited. We propose to study patients autonomic failure and low blood pressure upon standing and determine the cause of their disease by history and examination and their response to autonomic testing which have already been standardized in our laboratory. Based on their possible cause, we will tests different medications that may alleviate their symptoms.

Clinical Trial Conditions for MESTINON

Condition Name

Condition Name for MESTINON
Intervention	Trials
Diabetes Mellitus	3
Fibromyalgia	2
Orthostatic Hypotension	2

Condition MeSH

Condition MeSH for MESTINON
Intervention	Trials
Tachycardia	3
Postural Orthostatic Tachycardia Syndrome	3
HIV Infections	3

Clinical Trial Locations for MESTINON

Trials by Country

Trials by Country for MESTINON
Location	Trials
United States	12
Mexico	5
Denmark	2
Belgium	1
Switzerland	1

Trials by US State

Trials by US State for MESTINON
Location	Trials
New York	3
Tennessee	3
Florida	2
Virginia	1
Massachusetts	1

Clinical Trial Progress for MESTINON

Clinical Trial Phase

Clinical Trial Phase for MESTINON
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	1
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for MESTINON
Clinical Trial Phase	Trials
Completed	10
Recruiting	2
Active, not recruiting	2

Clinical Trial Sponsors for MESTINON

Sponsor Name

Sponsor Name for MESTINON
Sponsor	Trials
Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran	3
Vanderbilt University Medical Center	2
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	2

Sponsor Type

Sponsor Type for MESTINON
Sponsor	Trials
Other	34
NIH	8
Industry	1