A Study Designed to Determine if the Pharmacokinetic Disposition of Inhaled Insulin Exposure is the Same for Asthmatics and Non-asthmatics
Completed
Mannkind Corporation
Phase 1
2008-05-01
This study will compare the rate and extent of absorption of TI Inhalation Powder in subjects
with asthma and subjects with normal lung function. 24 eligible subjects will be enrolled
into the treatment phase of the trial.
Change in Airway Responsiveness After Allergen Exposure
Completed
University of Saskatchewan
N/A
2012-10-01
Exposure to allergens changes the way the airway responds to some stimuli (methacholine). The
investigators will look at whether or not exposure to allergens changes the way the airway
responds to a different stimuli (mannitol) and compare that with the known stimuli
(methacholine).
To examine whether a breathing test (methacholine challenge using impulse oscillometry) can
be used to tell the difference between two different doses of an inhaled drug, salmeterol,
delivered by Advair in children with asthma
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