Methylphenidate in Treating Patients With Melanoma
Completed
National Cancer Institute (NCI)
Phase 3
1999-06-01
RATIONALE: Methylphenidate may relieve some of the side effects of chemotherapy in patients
with melanoma. It is not known whether receiving methylphenidate is more effective than
receiving no further therapy in treating patients with melanoma.
PURPOSE: Randomized phase III trial to determine if methylphenidate is more effective than no
further therapy for the relief of fatigue and drowsiness in treating patients with melanoma
who have received high-dose interferon alfa for 8-24 weeks.
Methylphenidate in Treating Patients With Melanoma
Completed
Eastern Cooperative Oncology Group
Phase 3
1999-06-01
RATIONALE: Methylphenidate may relieve some of the side effects of chemotherapy in patients
with melanoma. It is not known whether receiving methylphenidate is more effective than
receiving no further therapy in treating patients with melanoma.
PURPOSE: Randomized phase III trial to determine if methylphenidate is more effective than no
further therapy for the relief of fatigue and drowsiness in treating patients with melanoma
who have received high-dose interferon alfa for 8-24 weeks.
The purpose of this NIMH-sponsored pilot study is to collect information on the efficacy and
safety of drug treatments for children and adolescents who suffer from both ADHD and anxiety
disorders. Specifically, the study will examine the benefits of the stimulant medication both
alone and in combination with fluvoxamine, a selective serotonin reuptake inhibitor (SSRI)
that has antianxiety effects. Young people aged 6 to 17 diagnosed with these co-occurring
disorders may be eligible to participate.
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