CLINICAL TRIALS PROFILE FOR MILRINONE LACTATE IN DEXTROSE 5%

All Clinical Trials for MILRINONE LACTATE IN DEXTROSE 5%

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00446017 ↗	The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG	Completed	Deutsche Stiftung für Herzforschung	Phase 3	2003-06-01	Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support after coronary-artery-bypass-grafting. With respect to data derived from patients with sepsis shock and results from studies using phosphodiesterase-inhibitors prophylactically, the hypothesis is tested that adrenaline may be associated with unwarranted metabolic effects (hyperlactatemia and hyperglycemia) and renal dysfunction.
NCT00446017 ↗	The Effects of Adrenaline and Milrinone in Patients With Myocardial Dysfunction After CABG	Completed	University of Luebeck	Phase 3	2003-06-01	Myocardial dysfunction necessitating inotropic support is a typical complication after on-pump cardiac surgery. This prospective, randomized pilot-study analyses the metabolic and renal effects of the inotropes adrenaline and milrinone in patients needing inotropic support after coronary-artery-bypass-grafting. With respect to data derived from patients with sepsis shock and results from studies using phosphodiesterase-inhibitors prophylactically, the hypothesis is tested that adrenaline may be associated with unwarranted metabolic effects (hyperlactatemia and hyperglycemia) and renal dysfunction.
NCT00695929 ↗	Levosimendan in Congenital Cardiac Surgery	Completed	Cliniques universitaires Saint-Luc- Université Catholique de Louvain	N/A	2008-07-01	Many pediatric patients undergoing cardiac surgery under cardiopulmonary bypass for repair of complex congenital malformations, require inotropic support for low cardiac output syndrome. Milrinone through its positive inotropic and vasodilatory effects is widely used for this purpose. The aim of the study is to compare Milrinone with Levosimendan, a novel inotope with calcium-sensitizing properties. We hypothesized that using Levosimendan would result in reduced serum lactate through a higher cardiac index.

Clinical Trial Conditions for MILRINONE LACTATE IN DEXTROSE 5%

Condition Name

Condition Name for MILRINONE LACTATE IN DEXTROSE 5%
Intervention	Trials
Low Cardiac Output Syndrome	3
Acute Coronary Syndrome	1
Cardiac Output, Low	1

Condition MeSH

Condition MeSH for MILRINONE LACTATE IN DEXTROSE 5%
Intervention	Trials
Cardiac Output, Low	4
Syndrome	2
Hypertension	1

Clinical Trial Locations for MILRINONE LACTATE IN DEXTROSE 5%

Trials by Country

Trials by Country for MILRINONE LACTATE IN DEXTROSE 5%
Location	Trials
United States	2
Belgium	1
China	1
Canada	1

Trials by US State

Trials by US State for MILRINONE LACTATE IN DEXTROSE 5%
Location	Trials
Pennsylvania	1
Michigan	1

Clinical Trial Progress for MILRINONE LACTATE IN DEXTROSE 5%

Clinical Trial Phase

Clinical Trial Phase for MILRINONE LACTATE IN DEXTROSE 5%
Clinical Trial Phase	Trials
Phase 4	1
Phase 3	2
N/A	2

Clinical Trial Status

Clinical Trial Status for MILRINONE LACTATE IN DEXTROSE 5%
Clinical Trial Phase	Trials
Completed	3
Unknown status	1
Terminated	1

Clinical Trial Sponsors for MILRINONE LACTATE IN DEXTROSE 5%

Sponsor Name

Sponsor Name for MILRINONE LACTATE IN DEXTROSE 5%
Sponsor	Trials
Ottawa Heart Institute Research Corporation	1
Shanghai Children's Medical Center	1
Deutsche Stiftung für Herzforschung	1

Sponsor Type

Sponsor Type for MILRINONE LACTATE IN DEXTROSE 5%
Sponsor	Trials
Other	9
Industry	1