CLINICAL TRIALS PROFILE FOR MINOCIN

All Clinical Trials for MINOCIN

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00240513 ↗	Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin	Terminated	Stiefel, a GSK Company	Phase 4	2004-08-01	The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby increasing the therapeutic effect of the oral antibiotic.
NCT00240513 ↗	Study Comparing Acne in Patients Taking Oral Minocycline to Patients Taking Minocycline Plus Topical Tretinoin	Terminated	Derm Research @ 888 Inc.	Phase 4	2004-08-01	The use of oral antibiotics alone to treat inflammatory acne provides little to no long term therapeutic benefit. Acne relapse rates can be reduced by using topical tretinoin 0.01% in conjunction with minocycline, thereby increasing the therapeutic effect of the oral antibiotic.
NCT00355459 ↗	A Prospective Clinical Study Assessing the Effects of Tetracycline Antibiotic on Tear Film and Tear Lipid Composition Within a Population of Patients Diagnosed With Blepharitis and Dry Eye Disease	Withdrawn	University of Texas Southwestern Medical Center	N/A	2005-08-01	The purpose of this research project is to determine the effects of oral tetracycline such as Minocycline (Minocin) on tear film composition and tear lipid (meibomian gland secretions) characteristics in patients with chronic Blepharitis and associated dry eyes.
NCT00456677 ↗	Evaluation of the Utility of Minocycline as an Anti-Inflammatory Agent in the Treatment of Asthma	Completed	State University of New York - Downstate Medical Center	Phase 2	1996-06-01	Trial of effects of minocycline as "add-on" therapy to adults with asthma with a history of requiring at least one episode of oral steroid therapy to control the disease.
NCT00473083 ↗	Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer	Completed	Hoffmann-La Roche	Phase 2	2009-01-01	The purpose of this trial is to determine if rash caused by erlotinib can be successfully treated and if so to determine the optimal treatment approach. Hypothesis: Hypothesis 1: If the incidence of rash is 50% while on erlotinib, prophylactic monotherapy with minocycline can prevent occurrence in 50% of these patients. Hypothesis 2: Treatment of rash is successful in improving rash by at least one Grade in 80% of patients. Hypothesis 3: In patients with untreated rash, the rash will be self-limiting in 25% of patients, and 65% will be grade 1, 2A, and 2b. Ten percent will be grade 3 requiring treatment with monotherapy intervention.
NCT00473083 ↗	Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer	Completed	British Columbia Cancer Agency	Phase 2	2009-01-01	The purpose of this trial is to determine if rash caused by erlotinib can be successfully treated and if so to determine the optimal treatment approach. Hypothesis: Hypothesis 1: If the incidence of rash is 50% while on erlotinib, prophylactic monotherapy with minocycline can prevent occurrence in 50% of these patients. Hypothesis 2: Treatment of rash is successful in improving rash by at least one Grade in 80% of patients. Hypothesis 3: In patients with untreated rash, the rash will be self-limiting in 25% of patients, and 65% will be grade 1, 2A, and 2b. Ten percent will be grade 3 requiring treatment with monotherapy intervention.
NCT00536042 ↗	Open-Label Trial of the Use of Minocycline in the Treatment of Asthma	Completed	State University of New York - Downstate Medical Center	Phase 2	1997-10-01	The tetracycline minocycline has, in addition to its anti-infective properties, anti-inflammatory properties which may be of use in the treatment of asthma. This study evaluates the benefit of minocycline as add-on therapy for adults with asthma.

Clinical Trial Conditions for MINOCIN

Condition Name

Condition Name for MINOCIN
Intervention	Trials
Head And Neck Cancer	2
Healthy	2
Autism Spectrum Disorder	2
Lung Cancer	2

Condition MeSH

Condition MeSH for MINOCIN
Intervention	Trials
Depressive Disorder	5
Depression	5
Lung Neoplasms	4
Syndrome	3

Clinical Trial Locations for MINOCIN

Trials by Country

Trials by Country for MINOCIN
Location	Trials
United States	58
Canada	13
Germany	5
France	1
China	1

Trials by US State

Trials by US State for MINOCIN
Location	Trials
Texas	13
New York	7
North Carolina	5
Michigan	4
Missouri	3

Clinical Trial Progress for MINOCIN

Clinical Trial Phase

Clinical Trial Phase for MINOCIN
Clinical Trial Phase	Trials
Phase 4	3
Phase 3	3
Phase 2/Phase 3	1

Clinical Trial Status

Clinical Trial Status for MINOCIN
Clinical Trial Phase	Trials
Completed	25
Terminated	4
Unknown status	4

Clinical Trial Sponsors for MINOCIN

Sponsor Name

Sponsor Name for MINOCIN
Sponsor	Trials
National Cancer Institute (NCI)	11
M.D. Anderson Cancer Center	11
Innovative Medicines Initiative	3

Sponsor Type

Sponsor Type for MINOCIN
Sponsor	Trials
Other	60
Industry	14
NIH	13