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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR MITOTANE


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All Clinical Trials for MITOTANE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00001339 ↗ A Study of Combination Chemotherapy and Surgical Resection in the Treatment of Adrenocortical Carcinoma: Continuous Infusion Doxorubicin, Vincristine and Etoposide With Daily Mitotane Before and After Surgical Resection Completed National Cancer Institute (NCI) Phase 2 1993-08-01 Patients who have no response to preoperative chemotherapy and no residual disease following surgery on Regimen A are treated on Regimen B postoperatively. The following acronyms are used: DDD Mitotane, NSC-38721 DOX Doxorubicin, NSC-123127 VCR Vincristine, NSC-67574 VP-16 Etoposide, NSC-141540 Regimen A: 4-Drug Combination Chemotherapy followed by Surgery followed by 4-Drug Combination Chemotherapy. DDD/DOX/VCR/VP-16; followed by surgical debulking; followed by DDD/DOX/VCR/VP-16. Regimen B: Single-Agent Chemotherapy. DDD.
NCT00002921 ↗ S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery Terminated National Cancer Institute (NCI) Phase 2 1997-03-01 RATIONALE: Some tumors need growth factors produced by the body to keep growing. Suramin may interfere with the growth factor and stop the tumor from growing. PURPOSE: Phase II trial to study the effectiveness of suramin in treating patients with stage III or stage IV adrenocortical cancer.
NCT00002921 ↗ S9427, Suramin in Treating Patients With Stage III or Stage IV Adrenocortical Cancer Incurable by Surgery Terminated Southwest Oncology Group Phase 2 1997-03-01 RATIONALE: Some tumors need growth factors produced by the body to keep growing. Suramin may interfere with the growth factor and stop the tumor from growing. PURPOSE: Phase II trial to study the effectiveness of suramin in treating patients with stage III or stage IV adrenocortical cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for MITOTANE

Condition Name

Condition Name for MITOTANE
Intervention Trials
Adrenocortical Carcinoma 11
Adrenal Cortex Neoplasms 2
Stage III Adrenocortical Carcinoma 2
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Condition MeSH

Condition MeSH for MITOTANE
Intervention Trials
Adrenocortical Carcinoma 19
Carcinoma 17
Adrenal Cortex Neoplasms 4
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Clinical Trial Locations for MITOTANE

Trials by Country

Trials by Country for MITOTANE
Location Trials
United States 84
Canada 7
Italy 6
Brazil 3
Germany 3
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Trials by US State

Trials by US State for MITOTANE
Location Trials
Maryland 7
Michigan 6
Texas 5
Missouri 3
Massachusetts 3
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Clinical Trial Progress for MITOTANE

Clinical Trial Phase

Clinical Trial Phase for MITOTANE
Clinical Trial Phase Trials
Phase 4 1
Phase 3 5
Phase 2 16
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Clinical Trial Status

Clinical Trial Status for MITOTANE
Clinical Trial Phase Trials
Completed 8
Recruiting 6
Unknown status 3
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Clinical Trial Sponsors for MITOTANE

Sponsor Name

Sponsor Name for MITOTANE
Sponsor Trials
National Cancer Institute (NCI) 9
M.D. Anderson Cancer Center 3
Azienda Ospedaliera Spedali Civili di Brescia 3
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Sponsor Type

Sponsor Type for MITOTANE
Sponsor Trials
Other 35
NIH 9
Industry 5
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