Comparative Study of Rocuronium With Vecuronium (Study 71101)(COMPLETED)
Completed
Merck Sharp & Dohme Corp.
Phase 3
2003-02-01
This study was conducted to determine and compare the safety and effectiveness of two
neuromuscular blockers (rocuronium and vecuronium) at various doses in adults who are
undergoing general elective surgery with sevoflurane anesthesia.
Study participants received an intubating dose of a neuromuscular blocker (to enable
insertion of a tube through the nose or mouth into the trachea to provide artificial
ventilation). The intubating dose was followed by repeated bolus maintenance doses as needed,
to maintain muscle relaxation. The time it takes to reach maximal effect of the neuromuscular
blocker (onset time) after the intubating dose was measured and compared as the primary
outcome.
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