CLINICAL TRIALS PROFILE FOR NORPRAMIN

All Clinical Trials for NORPRAMIN

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00166114 ↗	Depression, Epinephrine, and Platelet Function	Completed	National Heart, Lung, and Blood Institute (NHLBI)	Phase 4	2002-02-01	Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses. What is not known is whether adult survivors of childhood adversity experience heightened negative emotions and increased physical responses due to altered norepinephrine or serotonin systems in their brains and bodies. The investigators expect to see that survivors of childhood adversity experience heightened negative emotions and increased physical responses to stress.
NCT00166114 ↗	Depression, Epinephrine, and Platelet Function	Completed	Emory University	Phase 4	2002-02-01	Men and women who have suffered sexual and/or physical abuse before the age of 12 are at increased risk for anxiety and mood disorders, other serious psychiatric disorders, and likely medical illnesses. What is not known is whether adult survivors of childhood adversity experience heightened negative emotions and increased physical responses due to altered norepinephrine or serotonin systems in their brains and bodies. The investigators expect to see that survivors of childhood adversity experience heightened negative emotions and increased physical responses to stress.
NCT00338962 ↗	Naltrexone & SSRI in Alcoholics With Depression/PTSD	Completed	Yale University	Phase 3	2001-10-01	The purpose of this study is to evaluate the efficacy of naltrexone in combination with an SSRI to reduce alcohol consumption in alcoholic patients with comorbid PTSD and depression. We hypothesize that the combination of naltrexone and SSRI will exhibit a greater decrease in alcohol consumption than that seen with treatment with SSRI alone, or with a combination of another class of antidepressant and naltrexone. We also hypothesize that SSRI will be effective in treating PTSD and depressive symptoms and naltrexone will be well tolerated.
NCT00456014 ↗	Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment	Completed	National Institute of Mental Health (NIMH)	N/A	2006-09-01	This study will use pre-treatment positron emission topography and functional magnetic resonance imaging scans of the brain to predict the most effective antidepressant treatment for people with major depressive disorder.
NCT00456014 ↗	Pre-Treatment Positron Emission Topography Scanning for Increasing Success in Antidepressant Treatment	Completed	New York State Psychiatric Institute	N/A	2006-09-01	This study will use pre-treatment positron emission topography and functional magnetic resonance imaging scans of the brain to predict the most effective antidepressant treatment for people with major depressive disorder.
NCT00913809 ↗	To Demonstrate the Relative Bioequivalency of Cord's 100 mg Desipramine HCL Tablets To Merrell Dow's 100 mg Norpramin Tablets	Completed	Sandoz	Phase 1	1987-12-01	To demonstrate the relative bioequivalency of Cord's 100 mg Desipramine HCl tablets to Merrell Dow's 100 mg Norpramin tablets.
NCT00914004 ↗	To Demonstrate the Relative Bioequivalency of Comparing Single 100 mg Doses Of Cord's 50 mg Desipramine HCL Tablets To Merrell Dow's 50 mg Norpramin Tablets	Completed	Sandoz	Phase 1	1969-12-31	To demonstrate the relative bioequivalency of comparing single 100 mg doses Of Cord's 50 mg Desipramine Hcl tablets to Merrell Dow's 50 mg Norpramin tablets.

Clinical Trial Conditions for NORPRAMIN

Condition Name

Condition Name for NORPRAMIN
Intervention	Trials
Depression	4
Alcoholism	2
Schizophrenia	1
DS Stage I Plasma Cell Myeloma	1

Condition MeSH

Condition MeSH for NORPRAMIN
Intervention	Trials
Depression	5
Depressive Disorder	2
Alcoholism	2
Small Cell Lung Carcinoma	1

Clinical Trial Locations for NORPRAMIN

Trials by Country

Trials by Country for NORPRAMIN
Location	Trials
United States	10
France	1

Trials by US State

Trials by US State for NORPRAMIN
Location	Trials
California	2
New York	2
South Carolina	1
New Hampshire	1
Michigan	1

Clinical Trial Progress for NORPRAMIN

Clinical Trial Phase

Clinical Trial Phase for NORPRAMIN
Clinical Trial Phase	Trials
Phase 4	2
Phase 3	1
Phase 2	2

Clinical Trial Status

Clinical Trial Status for NORPRAMIN
Clinical Trial Phase	Trials
Completed	8
Recruiting	1
Terminated	1

Clinical Trial Sponsors for NORPRAMIN

Sponsor Name

Sponsor Name for NORPRAMIN
Sponsor	Trials
Sandoz	2
University of South Carolina	1
Dartmouth-Hitchcock Medical Center	1

Sponsor Type

Sponsor Type for NORPRAMIN
Sponsor	Trials
Other	11
NIH	3
Industry	3