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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR NOVANTRONE

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All Clinical Trials for NOVANTRONE

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Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00002003 ↗	Phase II Study of Novantrone(R) (Mitoxantrone) and Etoposide in Patients With HIV Associated Large Cell and Immunoblastic Lymphomas	Completed	Lederle Laboratories	Phase 2	1969-12-31	To determine the efficacy and toxicity of the combination of mitoxantrone hydrochloride ( Novantrone ) and etoposide in the treatment of patients with HIV associated lymphomas.
NCT00002259 ↗	Phase II Study of Intravenous Novantrone(R) in the Treatment of AIDS Related Kaposi's Sarcoma	Completed	Lederle Laboratories	Phase 2	1969-12-31	To study the toxicity and efficacy of IV mitoxantrone hydrochloride (Novantrone) in AIDS-related Kaposi's sarcoma.
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	National Cancer Institute (NCI)	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002805 ↗	Combination Chemotherapy in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome	Completed	Children's Oncology Group	Phase 2	1997-08-01	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of combination chemotherapy in treating patients with acute myeloid leukemia or myelodysplastic syndrome in first relapse or who did not achieve first remission.
NCT00002835 ↗	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	National Cancer Institute (NCI)	Phase 3	1995-10-30	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
NCT00002835 ↗	Combination Chemotherapy in Treating Patients With Lymphoma	Completed	M.D. Anderson Cancer Center	Phase 3	1995-10-30	RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining chemotherapy with peripheral stem cell transplantation may allow the doctor to give higher doses of chemotherapy drugs and kill more cancer cells. PURPOSE: Randomized phase III trial to compare the effectiveness of two regimens of combination chemotherapy in treating patients who have intermediate-grade or immunoblastic lymphoma.
>Trial ID	>Title	>Status	>Sponsor	>Phase	>Start Date	>Summary

Clinical Trial Conditions for NOVANTRONE

Condition Name

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Condition Name for NOVANTRONE
Intervention	Trials
Recurrent Adult Acute Myeloid Leukemia	17
Acute Myeloid Leukemia	12
Adult Acute Myeloid Leukemia With Inv(16)(p13;q22)	10
Untreated Adult Acute Myeloid Leukemia	10
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Condition MeSH

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Condition MeSH for NOVANTRONE
Intervention	Trials
Leukemia	44
Leukemia, Myeloid, Acute	41
Leukemia, Myeloid	40
Lymphoma	13
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Clinical Trial Locations for NOVANTRONE

Trials by Country

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Trials by Country for NOVANTRONE
Location	Trials
United States	465
Canada	49
Australia	21
New Zealand	9
Puerto Rico	7
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Trials by US State

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Trials by US State for NOVANTRONE
Location	Trials
California	20
Washington	18
Texas	17
New York	16
Ohio	16
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Clinical Trial Progress for NOVANTRONE

Clinical Trial Phase

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Clinical Trial Phase for NOVANTRONE
Clinical Trial Phase	Trials
Phase 4	3
Phase 3	9
Phase 2	27
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Clinical Trial Status

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Clinical Trial Status for NOVANTRONE
Clinical Trial Phase	Trials
Completed	40
Terminated	11
Active, not recruiting	8
[disabled in preview]	10
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Clinical Trial Sponsors for NOVANTRONE

Sponsor Name

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Sponsor Name for NOVANTRONE
Sponsor	Trials
National Cancer Institute (NCI)	31
Children's Oncology Group	6
Fred Hutchinson Cancer Research Center	6
[disabled in preview]	10
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Sponsor Type

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Sponsor Type for NOVANTRONE
Sponsor	Trials
Other	56
Industry	31
NIH	31
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