CLINICAL TRIALS PROFILE FOR NUBEQA
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All Clinical Trials for NUBEQA
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT03878524 ↗ | Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial | Recruiting | Oregon Health and Science University | Phase 1 | 2020-04-01 | This phase Ib trial determines if samples from a patient's cancer can be tested to find combinations of drugs that provide clinical benefit for the kind of cancer the patient has. This study is also being done to understand why cancer drugs can stop working and how different cancers in different people respond to different types of therapy. |
| NCT03878524 ↗ | Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial | Recruiting | Prospect Creek Foundation | Phase 1 | 2020-04-01 | This phase Ib trial determines if samples from a patient's cancer can be tested to find combinations of drugs that provide clinical benefit for the kind of cancer the patient has. This study is also being done to understand why cancer drugs can stop working and how different cancers in different people respond to different types of therapy. |
| NCT03878524 ↗ | Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial | Recruiting | OHSU Knight Cancer Institute | Phase 1 | 2020-04-01 | This phase Ib trial determines if samples from a patient's cancer can be tested to find combinations of drugs that provide clinical benefit for the kind of cancer the patient has. This study is also being done to understand why cancer drugs can stop working and how different cancers in different people respond to different types of therapy. |
| NCT04157088 ↗ | Study to Compare the Effects of Drug Darolutamide and Drug Enzalutamide on Physical Function, Including Balance and Daily Activity, in Patients With Castration-resistant Prostate Cancer (CRPC) | Recruiting | Bayer | Phase 2 | 2019-12-17 | Researchers in this study want to compare the effects of drug darolutamide and drug enzalutamide on physical function, including balance and daily activity, in patients with castration-resistant prostate cancer (CRPC). Both darolutamide and enzalutamide are approved AR inhibitors used for the treatment of patients with CRPC. AR inhibitor is a substance that keeps androgens (male sex hormones) from binding to proteins called androgen receptors, which are found in normal prostate cells, some prostate cancer cells, and in some other cells. Preventing this binding blocks the effects of these hormones in the body and therefore keeps prostate cancer cells from growing. Patients participating this study will receive either darolutamide or enzalutamide tablets. To evaluate the physical function, patients will be asked to make some movements like rising from a chair, walking three meters, etc. Additionally, researchers also want to find out the survival of patients and if patients have fatigue (feeling tired), cognitive (learning and thinking) problems, or other medical problems during the trial. Brand name of darolutamide is Nubeqa; brand name of enzalutamide is Xtandi. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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