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Last Updated: November 22, 2024

CLINICAL TRIALS PROFILE FOR OMACETAXINE MEPESUCCINATE


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All Clinical Trials for OMACETAXINE MEPESUCCINATE

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002574 ↗ Homoharringtonine and Interferon Alfa in Treating Patients With Chronic Myelogenous Leukemia Completed National Cancer Institute (NCI) Phase 2 1994-09-01 Phase II trial to study the effectiveness of homoharringtonine and interferon alfa in treating patients with chronic myelogenous leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Interferon alfa may interfere with the growth of cancer cells. Combining chemotherapy with interferon alfa may kill more cancer cells.
NCT00003239 ↗ Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Completed National Cancer Institute (NCI) Phase 2 1998-03-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with cytarabine and homoharringtonine and biological therapy with interferon alfa in treating patients with chronic phase chronic myelogenous leukemia.
NCT00003239 ↗ Chemotherapy and Biological Therapy in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Completed M.D. Anderson Cancer Center Phase 2 1998-03-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining biological therapy with chemotherapy may kill more cancer cells. PURPOSE: Phase II trial to study the effectiveness of chemotherapy with cytarabine and homoharringtonine and biological therapy with interferon alfa in treating patients with chronic phase chronic myelogenous leukemia.
NCT00003694 ↗ Homoharringtonine Plus Low-Dose Cytarabine in Treating Patients With Newly Diagnosed Chronic Myelogenous Leukemia in Chronic Phase Completed National Cancer Institute (NCI) Phase 2 1999-03-01 Phase II trial to study the effectiveness of homoharringtonine plus low-dose cytarabine in treating patients who have newly diagnosed chronic phase chronic myelogenous leukemia. Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
NCT00006364 ↗ Homoharringtonine in Treating Patients With Chronic Phase Chronic Myelogenous Leukemia Completed National Cancer Institute (NCI) Phase 2 1999-11-01 Phase II trial to study the effectiveness of homoharringtonine in treating patients who have chronic phase chronic myelogenous leukemia. Drugs used in chemotherapy, such as homoharringtonine, work in different ways to stop cancer cells from dividing so they stop growing or die
NCT00114959 ↗ Homoharringtonine With Oral Gleevec in Chronic, Accelerated and Blast Phase Chronic Myeloid Leukemia (CML) Terminated ChemGenex Pharmaceuticals Phase 2 2005-10-01 This will be an open label, multi-center study of up to 77 patients with CML in chronic, accelerated or blast phase who have developed resistance to or have failed previous treatment with Gleevec (imatinib mesylate). Because these patients may still be sensitive to Gleevec, adding Homoharringtonine may restore a response to Gleevec or the combined treatment may promote a better response than using Gleevec alone.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for OMACETAXINE MEPESUCCINATE

Condition Name

Condition Name for OMACETAXINE MEPESUCCINATE
Intervention Trials
Chronic Myeloid Leukemia 3
Chronic Phase Chronic Myelogenous Leukemia 2
FLT3-ITD Mutation 2
AML 2
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Condition MeSH

Condition MeSH for OMACETAXINE MEPESUCCINATE
Intervention Trials
Leukemia 10
Leukemia, Myeloid 10
Leukemia, Myelogenous, Chronic, BCR-ABL Positive 8
Leukemia, Myeloid, Chronic-Phase 4
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Clinical Trial Locations for OMACETAXINE MEPESUCCINATE

Trials by Country

Trials by Country for OMACETAXINE MEPESUCCINATE
Location Trials
United States 33
France 3
Hungary 2
Poland 2
Hong Kong 2
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Trials by US State

Trials by US State for OMACETAXINE MEPESUCCINATE
Location Trials
Texas 9
New York 4
Indiana 3
Massachusetts 3
Pennsylvania 2
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Clinical Trial Progress for OMACETAXINE MEPESUCCINATE

Clinical Trial Phase

Clinical Trial Phase for OMACETAXINE MEPESUCCINATE
Clinical Trial Phase Trials
Phase 2 10
Phase 1/Phase 2 4
Phase 1 2
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Clinical Trial Status

Clinical Trial Status for OMACETAXINE MEPESUCCINATE
Clinical Trial Phase Trials
Completed 9
Terminated 4
Not yet recruiting 1
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Clinical Trial Sponsors for OMACETAXINE MEPESUCCINATE

Sponsor Name

Sponsor Name for OMACETAXINE MEPESUCCINATE
Sponsor Trials
National Cancer Institute (NCI) 5
ChemGenex Pharmaceuticals 4
Teva Branded Pharmaceutical Products R&D, Inc. 4
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Sponsor Type

Sponsor Type for OMACETAXINE MEPESUCCINATE
Sponsor Trials
Industry 16
Other 7
NIH 5
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