CLINICAL TRIALS PROFILE FOR ORAPRED ODT

All Clinical Trials for ORAPRED ODT

Trial ID	Title	Status	Sponsor	Phase	Start Date	Summary
NCT00079105 ↗	A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years	Completed	Newcastle-upon-Tyne Hospitals NHS Trust	Phase 2	2004-01-01	RATIONALE: Drugs used in chemotherapy, such as vinblastine, cyclophosphamide, procarbazine, prednisolone, etoposide, mitoxantrone, and bleomycin, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug may kill more cancer cells. PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating older patients with previously untreated Hodgkin's lymphoma.
NCT00798616 ↗	Steroids Helping Albuterol Responders Exclusively	Withdrawn	University Hospitals Cleveland Medical Center	N/A	1969-12-31	The purpose of the study is to determine whether corticosteroids are beneficial to children with bronchiolitis whose breathing gets better after being given a breathing treatment with albuterol.
NCT01211665 ↗	Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)	Terminated	Elan Pharmaceuticals	Phase 4	2010-09-01	The objectives of this study are to explore the effects of administering high-dose corticosteroids to participants who developed progressive multifocal leukoencephalopathy (PML) while on natalizumab as measured by time-course change in functional status based on Karnofsky Performance Status Index through 6 months following the completion of plasma exchange (PLEX; or equivalent), survival at 6 months following the completion of PLEX (or equivalent), and incidence and severity of adverse events (AEs) and serious adverse events (SAEs); to characterize the evolution of immune reconstitution inflammatory syndrome (IRIS) as measured by time course changes in Global Clinical Impression of Improvement (GCI-I), Symbol Digit Modalities Test (SDMT), brain magnetic resonance imaging (MRI), magnetoencephalography (MEG), chemokines, cytokines, C-reactive protein (CRP), John Cunningham virus (JCV) load and cell count in cerebrospinal fluid (CSF); and to characterize the time course elimination of serum natalizumab concentrations in the study population following the last PLEX (or equivalent) procedure.
NCT01211665 ↗	Corticosteroids for Immune Reconstitution Inflammatory Syndrome (IRIS)	Terminated	Biogen	Phase 4	2010-09-01	The objectives of this study are to explore the effects of administering high-dose corticosteroids to participants who developed progressive multifocal leukoencephalopathy (PML) while on natalizumab as measured by time-course change in functional status based on Karnofsky Performance Status Index through 6 months following the completion of plasma exchange (PLEX; or equivalent), survival at 6 months following the completion of PLEX (or equivalent), and incidence and severity of adverse events (AEs) and serious adverse events (SAEs); to characterize the evolution of immune reconstitution inflammatory syndrome (IRIS) as measured by time course changes in Global Clinical Impression of Improvement (GCI-I), Symbol Digit Modalities Test (SDMT), brain magnetic resonance imaging (MRI), magnetoencephalography (MEG), chemokines, cytokines, C-reactive protein (CRP), John Cunningham virus (JCV) load and cell count in cerebrospinal fluid (CSF); and to characterize the time course elimination of serum natalizumab concentrations in the study population following the last PLEX (or equivalent) procedure.
NCT01391793 ↗	Corticosteroids for Children With Febrile Urinary Tract Infections	Completed	National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)	Phase 3	2011-09-01	In this study the investigators will determine whether corticosteroids given at the time of urinary tract infection help prevent permanent damage to the kidneys.
NCT01391793 ↗	Corticosteroids for Children With Febrile Urinary Tract Infections	Completed	Nader Shaikh	Phase 3	2011-09-01	In this study the investigators will determine whether corticosteroids given at the time of urinary tract infection help prevent permanent damage to the kidneys.
NCT01391793 ↗	Corticosteroids for Children With Febrile Urinary Tract Infections	Completed	University of Pittsburgh	Phase 3	2011-09-01	In this study the investigators will determine whether corticosteroids given at the time of urinary tract infection help prevent permanent damage to the kidneys.

Clinical Trial Conditions for ORAPRED ODT

Condition Name

Condition Name for ORAPRED ODT
Intervention	Trials
Transplantation, Cornea	1
Immune Reconstitution Inflammatory Syndrome	1
Transplantation, Corneal	1
Keratoplasty	1

Condition MeSH

Condition MeSH for ORAPRED ODT
Intervention	Trials
Asthma	1
Bronchiolitis	1
Infection	1
Stomatitis	1

Clinical Trial Locations for ORAPRED ODT

Trials by Country

Trials by Country for ORAPRED ODT
Location	Trials
United States	12
United Kingdom	3
Germany	2
Thailand	1

Trials by US State

Trials by US State for ORAPRED ODT
Location	Trials
Ohio	2
Florida	1
Oregon	1
California	1
Texas	1

Clinical Trial Progress for ORAPRED ODT

Clinical Trial Phase

Clinical Trial Phase for ORAPRED ODT
Clinical Trial Phase	Trials
Phase 4	3
Phase 3	1
Phase 2	2

Clinical Trial Status

Clinical Trial Status for ORAPRED ODT
Clinical Trial Phase	Trials
Completed	3
Terminated	2
Active, not recruiting	2

Clinical Trial Sponsors for ORAPRED ODT

Sponsor Name

Sponsor Name for ORAPRED ODT
Sponsor	Trials
Novartis Pharmaceuticals	1
US Oncology Research	1
Stanford University	1

Sponsor Type

Sponsor Type for ORAPRED ODT
Sponsor	Trials
Other	10
Industry	4
NIH	1