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Last Updated: November 4, 2024

CLINICAL TRIALS PROFILE FOR PEDIAPRED


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All Clinical Trials for PEDIAPRED

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00004228 ↗ Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma Completed National Cancer Institute (NCI) Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for lymphoblastic lymphoma. PURPOSE: This randomized phase III trial is studying different regimens of combination chemotherapy to compare how well they work in treating children or adolescents with newly diagnosed stage III or stage IV lymphoblastic lymphoma.
NCT00004228 ↗ Combination Chemotx in Treating Children or Adolescents With Newly Diagnosed Stg III or Stg IV Lymphoblastic Lymphoma Completed Children's Oncology Group Phase 3 2000-06-01 RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. It is not yet known which regimen of combination chemotherapy is most effective for lymphoblastic lymphoma. PURPOSE: This randomized phase III trial is studying different regimens of combination chemotherapy to compare how well they work in treating children or adolescents with newly diagnosed stage III or stage IV lymphoblastic lymphoma.
NCT00066469 ↗ Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ Transplantation Completed National Cancer Institute (NCI) Phase 2 2004-04-01 RATIONALE: Drugs used in chemotherapy such as cyclophosphamide, prednisone, and methylprednisolone use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining cyclophosphamide and either prednisone or methylprednisolone with rituximab may be effective in treating lymphoproliferative disease following organ transplantation. PURPOSE: Phase II trial to study the effectiveness of combining cyclophosphamide and either prednisone or methylprednisolone with rituximab in treating patients who have Epstein-Barr virus-positive lymphoproliferative disease following organ transplantation.
NCT00066469 ↗ Cyclophosphamide, Rituximab, and Either Prednisone or Methylprednisolone in Treating Patients With Lymphoproliferative Disease After Solid Organ Transplantation Completed Children's Oncology Group Phase 2 2004-04-01 RATIONALE: Drugs used in chemotherapy such as cyclophosphamide, prednisone, and methylprednisolone use different ways to stop cancer cells from dividing so they stop growing or die. Monoclonal antibodies such as rituximab can locate cancer cells and either kill them or deliver cancer-killing substances to them without harming normal cells. Combining cyclophosphamide and either prednisone or methylprednisolone with rituximab may be effective in treating lymphoproliferative disease following organ transplantation. PURPOSE: Phase II trial to study the effectiveness of combining cyclophosphamide and either prednisone or methylprednisolone with rituximab in treating patients who have Epstein-Barr virus-positive lymphoproliferative disease following organ transplantation.
NCT00079105 ↗ A Phase II Study VEPEMB In Patients With Hodgkin's Lymphoma Aged ≥ 60 Years Completed Newcastle-upon-Tyne Hospitals NHS Trust Phase 2 2004-01-01 RATIONALE: Drugs used in chemotherapy, such as vinblastine, cyclophosphamide, procarbazine, prednisolone, etoposide, mitoxantrone, and bleomycin, work in different ways to stop cancer cells from dividing so they stop growing or die. Combining more than one chemotherapy drug may kill more cancer cells. PURPOSE: This phase II trial is studying how well combination chemotherapy works in treating older patients with previously untreated Hodgkin's lymphoma.
NCT00796250 ↗ Efficacy of Infliximab in the Treatment of Patients Affected by Corticodependent Crohn's Disease (P02732) Terminated Merck Sharp & Dohme Corp. Phase 3 2003-11-01 This is a double-blind, double-dummy, prednisolone-controlled, multi-center, randomized, parallel-group clinical study to evaluate the therapeutic efficacy of repeated infliximab infusions in order to maintain Crohn's disease remission at the end of the study.
NCT00967226 ↗ Propranolol Versus Prednisolone for Treatment of Symptomatic Hemangiomas Terminated Nancy Bauman Phase 2 2009-07-01 Hemangiomas are relatively common lesions in infants. Most go away spontaneously after one year of life and do not need treatment. Others require treatment because they cause significant symptoms such as pain, or difficulty with breathing, eating or ambulating. Steroids have classically been used to treat hemangiomas and help to shrink them in 1/3 - 2/3 of patients. Unfortunately, steroids have many side effects in babies so physicians have sought other ways to treat them. Recently, the use of propranolol, a heart medication, was serendipitously found to reduce the size of hemangiomas. It appears to have many fewer side effects than steroids but it is not yet known if it works as well as steroids. This study seeks to compare the effect and the side effects of propranolol versus steroids for treating hemangiomas that cause symptoms in infants.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for PEDIAPRED

Condition Name

Condition Name for PEDIAPRED
Intervention Trials
Lymphoma 2
Canavan Disease 1
Crohn's Disease 1
Hemangioma of Infancy 1
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Condition MeSH

Condition MeSH for PEDIAPRED
Intervention Trials
Lymphoma 2
Lymphoproliferative Disorders 1
Precursor Cell Lymphoblastic Leukemia-Lymphoma 1
Lymphoma, Non-Hodgkin 1
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Clinical Trial Locations for PEDIAPRED

Trials by Country

Trials by Country for PEDIAPRED
Location Trials
United States 81
Canada 15
Australia 8
United Kingdom 3
New Zealand 1
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Trials by US State

Trials by US State for PEDIAPRED
Location Trials
Ohio 3
Michigan 2
Louisiana 2
Kentucky 2
Wisconsin 2
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Clinical Trial Progress for PEDIAPRED

Clinical Trial Phase

Clinical Trial Phase for PEDIAPRED
Clinical Trial Phase Trials
Phase 3 2
Phase 2 3
Phase 1/Phase 2 1
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Clinical Trial Status

Clinical Trial Status for PEDIAPRED
Clinical Trial Phase Trials
Completed 3
Terminated 2
Recruiting 1
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Clinical Trial Sponsors for PEDIAPRED

Sponsor Name

Sponsor Name for PEDIAPRED
Sponsor Trials
National Cancer Institute (NCI) 2
Children's Oncology Group 2
Myrtelle Inc. 1
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Sponsor Type

Sponsor Type for PEDIAPRED
Sponsor Trials
Other 4
Industry 3
NIH 2
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