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Last Updated: November 5, 2024

CLINICAL TRIALS PROFILE FOR PEMETREXED


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All Clinical Trials for PEMETREXED

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00003711 ↗ Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors Completed San Antonio Cancer Institute Phase 1 1997-09-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with pemetrexed disodium and irinotecan in treating patients who have metastatic solid tumors.
NCT00005636 ↗ Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery Completed National Cancer Institute (NCI) Phase 3 1999-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if cisplatin is more effective with or without pemetrexed disodium for malignant mesothelioma of the pleura. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that cannot be removed by surgery.
NCT00005636 ↗ Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery Completed Memorial Sloan Kettering Cancer Center Phase 3 1999-11-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. It is not yet known if cisplatin is more effective with or without pemetrexed disodium for malignant mesothelioma of the pleura. PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that cannot be removed by surgery.
NCT00006007 ↗ LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer Completed National Cancer Institute (NCI) Phase 2 2000-12-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining LY231514 plus gemcitabine in treating women who have metastatic breast cancer.
NCT00006007 ↗ LY231514 Plus Gemcitabine in Treating Women With Metastatic Breast Cancer Completed Alliance for Clinical Trials in Oncology Phase 2 2000-12-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells. PURPOSE: Phase II trial to study the effectiveness of combining LY231514 plus gemcitabine in treating women who have metastatic breast cancer.
NCT00022646 ↗ Pemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Completed National Cancer Institute (NCI) Phase 2 2001-08-01 RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving more than one drug and giving the drugs in different ways may kill more tumor cells. PURPOSE: Randomized phase II trial to compare the effectiveness of three different regimens of pemetrexed disodium plus gemcitabine in treating patients who have locally advanced or metastatic non-small cell lung cancer.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for PEMETREXED

Condition Name

Condition Name for PEMETREXED
Intervention Trials
Non-Small Cell Lung Cancer 151
Lung Cancer 78
Non Small Cell Lung Cancer 76
Carcinoma, Non-Small-Cell Lung 63
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Condition MeSH

Condition MeSH for PEMETREXED
Intervention Trials
Carcinoma, Non-Small-Cell Lung 595
Lung Neoplasms 549
Mesothelioma 99
Mesothelioma, Malignant 94
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Clinical Trial Locations for PEMETREXED

Trials by Country

Trials by Country for PEMETREXED
Location Trials
China 514
Italy 374
Spain 346
Japan 317
Netherlands 92
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Trials by US State

Trials by US State for PEMETREXED
Location Trials
California 191
New York 175
Texas 173
Florida 167
Pennsylvania 165
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Clinical Trial Progress for PEMETREXED

Clinical Trial Phase

Clinical Trial Phase for PEMETREXED
Clinical Trial Phase Trials
Phase 4 17
Phase 3 178
Phase 2/Phase 3 20
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Clinical Trial Status

Clinical Trial Status for PEMETREXED
Clinical Trial Phase Trials
Completed 354
Recruiting 188
Not yet recruiting 123
[disabled in preview] 263
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Clinical Trial Sponsors for PEMETREXED

Sponsor Name

Sponsor Name for PEMETREXED
Sponsor Trials
Eli Lilly and Company 168
National Cancer Institute (NCI) 108
Merck Sharp & Dohme Corp. 47
[disabled in preview] 101
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Sponsor Type

Sponsor Type for PEMETREXED
Sponsor Trials
Other 764
Industry 660
NIH 108
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