Combination Chemotherapy in Treating Patients With Metastatic Solid Tumors
Completed
San Antonio Cancer Institute
Phase 1
1997-09-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. Combining more than one drug may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of combination chemotherapy with pemetrexed
disodium and irinotecan in treating patients who have metastatic solid tumors.
Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery
Completed
National Cancer Institute (NCI)
Phase 3
1999-11-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. It is not yet known if cisplatin is more effective with or without
pemetrexed disodium for malignant mesothelioma of the pleura.
PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without
pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that
cannot be removed by surgery.
Cisplatin With or Without Pemetrexed Disodium in Treating Patients With Malignant Mesothelioma of the Pleura That Cannot be Removed by Surgery
Completed
Memorial Sloan Kettering Cancer Center
Phase 3
1999-11-01
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so
they stop growing or die. It is not yet known if cisplatin is more effective with or without
pemetrexed disodium for malignant mesothelioma of the pleura.
PURPOSE: Randomized phase III trial to compare the effectiveness of cisplatin with or without
pemetrexed disodium in treating patients who have malignant mesothelioma of the pleura that
cannot be removed by surgery.
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