CLINICAL TRIALS PROFILE FOR PEXIDARTINIB HYDROCHLORIDE
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All Clinical Trials for PEXIDARTINIB HYDROCHLORIDE
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT01349036 ↗ | A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma | Terminated | Plexxikon | Phase 2 | 2011-12-03 | The objective of this study is to evaluate the response of subjects with recurrent glioblastoma to continuous therapy of PLX3397. |
NCT01349036 ↗ | A Phase 2 Study of PLX3397 in Patients With Recurrent Glioblastoma | Terminated | Daiichi Sankyo, Inc. | Phase 2 | 2011-12-03 | The objective of this study is to evaluate the response of subjects with recurrent glioblastoma to continuous therapy of PLX3397. |
NCT01525602 ↗ | Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors | Completed | Plexxikon | Phase 1 | 2012-05-01 | This was a 3-part study designed to explore the safety and tolerability of escalating doses of PLX3397 with weekly paclitaxel to establish a recommended Phase 2 dose (RP2D), to confirm RP2D in participants with advanced non-resectable solid tumors, and to determine the efficacy of PLX3397 600 mg twice daily (BID) administered in combination with weekly paclitaxel in participants with advanced, metastatic or non-resectable, platinum-resistant or -refractory epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. |
NCT01525602 ↗ | Safety Study of PLX3397 and Paclitaxel in Patients With Advanced Solid Tumors | Completed | Daiichi Sankyo, Inc. | Phase 1 | 2012-05-01 | This was a 3-part study designed to explore the safety and tolerability of escalating doses of PLX3397 with weekly paclitaxel to establish a recommended Phase 2 dose (RP2D), to confirm RP2D in participants with advanced non-resectable solid tumors, and to determine the efficacy of PLX3397 600 mg twice daily (BID) administered in combination with weekly paclitaxel in participants with advanced, metastatic or non-resectable, platinum-resistant or -refractory epithelial ovarian cancer, primary peritoneal cancer, or fallopian tube cancer. |
NCT01790503 ↗ | A Phase 1b/2 Study of PLX3397 + Radiation Therapy + Temozolomide in Patients With Newly Diagnosed Glioblastoma | Completed | Plexxikon | Phase 1/Phase 2 | 2013-07-18 | The study objectives are to assess the potential for PLX3397 to improve the efficacy of standard of care radiation therapy (RT) + temozolomide in patients with newly diagnosed glioblastoma (GBM). |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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