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Last Updated: December 23, 2024

CLINICAL TRIALS PROFILE FOR PHOTOFRIN


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All Clinical Trials for PHOTOFRIN

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00002935 ↗ Photodynamic Therapy in Treating Patients With Early Esophageal Cancer Completed Roswell Park Cancer Institute Phase 2 1995-10-01 RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be an effective treatment for esophageal cancer. PURPOSE: Phase II trial to study the effectiveness of photodynamic therapy in treating patients with Barrett's esophagus who have in situ esophageal cancer.
NCT00002964 ↗ Porfimer Sodium in Diagnosing Patients With Head and Neck Cancer Completed Roswell Park Cancer Institute Phase 2 1995-02-01 RATIONALE: Drugs that make cancer cells more visible to light may help in the diagnosis of head and neck cancer. PURPOSE: Phase II trial to study the usefulness of porfimer sodium in diagnosing patients with head and neck cancer.
NCT00003788 ↗ Surgery, Radiation Therapy, and Chemotherapy With or Without Photodynamic Therapy in Treating Patients With Newly Diagnosed or Recurrent Malignant Supratentorial Gliomas Unknown status Colorado Health Foundation Phase 3 1998-04-01 RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. It is not yet known if the addition of photodynamic therapy to combined therapy with surgery, radiation therapy, and chemotherapy is more effective than combined therapy alone for supratentorial gliomas. PURPOSE: Randomized phase III trial to study the effectiveness of surgery, radiation therapy, and chemotherapy with or without photodynamic therapy in treating patients who have newly diagnosed or recurrent malignant supratentorial gliomas.
NCT00003923 ↗ Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas Completed National Cancer Institute (NCI) Phase 2 1999-03-01 RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be effective treatment for cancer of the bile duct, gallbladder, or pancreas. PURPOSE: Phase II trial to determine the effectiveness of photodynamic therapy in treating patients who have cancer of the bile duct, gallbladder, or pancreas.
NCT00003923 ↗ Photodynamic Therapy in Treating Patients With Cancer of the Bile Duct, Gallbladder, or Pancreas Completed Memorial Sloan Kettering Cancer Center Phase 2 1999-03-01 RATIONALE: Photodynamic therapy uses light and drugs that make cancer cells more sensitive to light to kill tumor cells. This may be effective treatment for cancer of the bile duct, gallbladder, or pancreas. PURPOSE: Phase II trial to determine the effectiveness of photodynamic therapy in treating patients who have cancer of the bile duct, gallbladder, or pancreas.
NCT00014066 ↗ Photodynamic Therapy Plus Brachytherapy in Treating Patients With Lung Cancer Completed Roswell Park Cancer Institute Phase 1 1993-03-01 RATIONALE: Photodynamic therapy uses light and drugs that make cnacer cells more sensitive to light to kill tumor cells. Brachytherapy uses radiation to damage tumor cells. Photodynamic therapy combined with brachytherapy may kill more tumor cells. PURPOSE: Phase I trial to study the effectiveness of photodynamic therapy plus brachytherapy in treating patients with recurrent lung cancer that is blocking the lung passages.
NCT00118222 ↗ High Light and Low Light Dose PDT in Glioma Completed National Cancer Institute (NCI) Phase 3 2005-03-01 RATIONALE: Photodynamic therapy uses a drug, such as porfimer sodium, that becomes active when it is exposed to a certain kind of light. When the drug is active, tumor cells are killed. Giving photodynamic therapy after surgery may kill any remaining tumor cells. PURPOSE: This randomized clinical trial is studying two different light doses of photodynamic therapy using porfimer sodium to compare how well they work in treating patients who are undergoing surgery for recurrent malignant astrocytoma.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for PHOTOFRIN

Condition Name

Condition Name for PHOTOFRIN
Intervention Trials
Lung Cancer 3
Head and Neck Cancer 3
Brain Tumor, Recurrent 2
Lung Metastasis 2
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Condition MeSH

Condition MeSH for PHOTOFRIN
Intervention Trials
Lung Neoplasms 8
Carcinoma, Non-Small-Cell Lung 5
Head and Neck Neoplasms 4
Mesothelioma, Malignant 4
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Clinical Trial Locations for PHOTOFRIN

Trials by Country

Trials by Country for PHOTOFRIN
Location Trials
United States 46
Korea, Republic of 5
Canada 4
Germany 4
Switzerland 1
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Trials by US State

Trials by US State for PHOTOFRIN
Location Trials
New York 11
Pennsylvania 5
Florida 4
Washington 3
Wisconsin 3
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Clinical Trial Progress for PHOTOFRIN

Clinical Trial Phase

Clinical Trial Phase for PHOTOFRIN
Clinical Trial Phase Trials
Phase 3 4
Phase 2 9
Phase 1/Phase 2 2
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Clinical Trial Status

Clinical Trial Status for PHOTOFRIN
Clinical Trial Phase Trials
Completed 13
Terminated 5
Recruiting 4
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Clinical Trial Sponsors for PHOTOFRIN

Sponsor Name

Sponsor Name for PHOTOFRIN
Sponsor Trials
Roswell Park Cancer Institute 7
National Cancer Institute (NCI) 6
Pinnacle Biologics Inc. 4
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Sponsor Type

Sponsor Type for PHOTOFRIN
Sponsor Trials
Other 29
Industry 9
NIH 6
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