CLINICAL TRIALS PROFILE FOR PIFELTRO
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All Clinical Trials for PIFELTRO
Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
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NCT03886701 ↗ | Doravirine, Rifapentine and Isoniazid Interaction | Completed | Merck Sharp & Dohme Corp. | Phase 1 | 2019-04-22 | Drug therapy for persons living with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) co-infected with latent tuberculosis infection (LTBI) is complex. Anti-tuberculosis drugs used to treat LTBI often induce drug metabolizing enzymes that share the same metabolic pathway as antiretroviral drugs used for those living with HIV/AIDS. This study evaluates the drug-drug interaction (DDI) potential of an antiretroviral drug when co-administered with a common anti-tuberculosis regimen of drugs. |
NCT03886701 ↗ | Doravirine, Rifapentine and Isoniazid Interaction | Completed | Walter K. Kraft | Phase 1 | 2019-04-22 | Drug therapy for persons living with human immunodeficiency virus (HIV) or acquired immunodeficiency syndrome (AIDS) co-infected with latent tuberculosis infection (LTBI) is complex. Anti-tuberculosis drugs used to treat LTBI often induce drug metabolizing enzymes that share the same metabolic pathway as antiretroviral drugs used for those living with HIV/AIDS. This study evaluates the drug-drug interaction (DDI) potential of an antiretroviral drug when co-administered with a common anti-tuberculosis regimen of drugs. |
NCT03894124 ↗ | Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers | Completed | Imperial College London | Phase 1 | 2019-06-12 | Study to assess the pharmacokinetics of plasma doravirine once daily over 72 hours following drug intake cessation at steady-state in healthy volunteers |
NCT03894124 ↗ | Pharmacokinetics of Plasma Doravirine Once Daily Over 72 Hours Following Drug Intake Cessation in Healthy Volunteers | Completed | Merck Sharp & Dohme Corp. | Phase 1 | 2019-06-12 | Study to assess the pharmacokinetics of plasma doravirine once daily over 72 hours following drug intake cessation at steady-state in healthy volunteers |
>Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for PIFELTRO
Condition Name
Condition Name for PIFELTRO | |
Intervention | Trials |
Human Immunodeficiency Virus | 2 |
Drug Interaction Potentiation | 1 |
HIV-1-infection | 1 |
HIV-infected Participants With ESRD Undergoing Routine Hemodialysis | 1 |
[disabled in preview] | 0 |
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Clinical Trial Locations for PIFELTRO
Trials by Country
Clinical Trial Progress for PIFELTRO
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Clinical Trial Sponsors for PIFELTRO
Sponsor Name