Effects of Atorvastatin Versus Probucol on Small Dense LDL
Completed
Yokohama City University Medical Center
Phase 4
2004-01-01
Small dense low-density lipoprotein (LDL) plays an important role in causing glomerular
injury through conversion to an oxidatively modified form of LDL. However, few studies
evaluated the effects of antilipidemic agents on the LDL particle size and renoprotective
actions in hyperlipidemic patients with non-diabetic nephropathy.
A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy
Completed
Guangdong General Hospital
Phase 4
2007-05-01
a statement of the study hypothesis:the effect of valsartan in patients with IgA nephropathy
have been proved,and the efficacy of probucol in combination with valsartan is to be proved
in patients with IgA nephropathy.
This is a prospective randomized controlled, double blinded pilot study to identify the
efficacy of probucol in combination with valsartan in patients with IgA nephropathy. The
renal function deterioration will be the primary outcome studied. The expected study duration
will be 36 months.
A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy
Completed
Guangdong Provincial People's Hospital
Phase 4
2007-05-01
a statement of the study hypothesis:the effect of valsartan in patients with IgA nephropathy
have been proved,and the efficacy of probucol in combination with valsartan is to be proved
in patients with IgA nephropathy.
This is a prospective randomized controlled, double blinded pilot study to identify the
efficacy of probucol in combination with valsartan in patients with IgA nephropathy. The
renal function deterioration will be the primary outcome studied. The expected study duration
will be 36 months.
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