Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)
Completed
National Heart, Lung, and Blood Institute (NHLBI)
Phase 3
1987-04-01
To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals
who had survived one episode of out-of-hospital cardiac arrest.
Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE)
Completed
University of Washington
Phase 3
1987-04-01
To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals
who had survived one episode of out-of-hospital cardiac arrest.
Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
Completed
National Heart, Lung, and Blood Institute (NHLBI)
Phase 3
1985-07-01
To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better
method for selecting effective long-term antiarrhythmic drug therapy in patients with
sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden
death.
Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM)
Completed
University of Utah
Phase 3
1985-07-01
To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better
method for selecting effective long-term antiarrhythmic drug therapy in patients with
sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden
death.
Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM)
Completed
National Heart, Lung, and Blood Institute (NHLBI)
Phase 3
1995-03-01
To compare two standard treatment strategies for atrial fibrillation: ventricular rate
control and anticoagulation vs. rhythm control and anticoagulation.
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