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Last Updated: December 24, 2024

CLINICAL TRIALS PROFILE FOR QUESTRAN


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All Clinical Trials for QUESTRAN

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01053065 ↗ The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study Completed Biomedical Foundation for Cardiovascular Research of Padova N/A 1969-12-31 The impact on cardiovascular events achieved by statin therapy seems to be mostly attributable to the cholesterol-lowering effect with a highly debated contribution of the lipid-independent pleiotropic effects. However, a short-term benefit has been documented for patients treated with statins in acute coronary syndromes and other clinical settings. These observations strengthened the hypothesis of additional, so-called pleiotropic actions of statins. The investigators therefore sought to investigate how different lipid-lowering strategies (non-statin therapy, low-dose statin and high-dose statin) affects cellular composition of carotid plaque over a short-term period of three months. Specifically the investigators tried and dissect the LDL-C lowering impact on plaque cellular composition as compared to the lipid-independent contribution on plaque macrophage and smooth muscle cells.
NCT01053065 ↗ The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study Completed Pfizer N/A 1969-12-31 The impact on cardiovascular events achieved by statin therapy seems to be mostly attributable to the cholesterol-lowering effect with a highly debated contribution of the lipid-independent pleiotropic effects. However, a short-term benefit has been documented for patients treated with statins in acute coronary syndromes and other clinical settings. These observations strengthened the hypothesis of additional, so-called pleiotropic actions of statins. The investigators therefore sought to investigate how different lipid-lowering strategies (non-statin therapy, low-dose statin and high-dose statin) affects cellular composition of carotid plaque over a short-term period of three months. Specifically the investigators tried and dissect the LDL-C lowering impact on plaque cellular composition as compared to the lipid-independent contribution on plaque macrophage and smooth muscle cells.
NCT01053065 ↗ The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study Completed University of Padova N/A 1969-12-31 The impact on cardiovascular events achieved by statin therapy seems to be mostly attributable to the cholesterol-lowering effect with a highly debated contribution of the lipid-independent pleiotropic effects. However, a short-term benefit has been documented for patients treated with statins in acute coronary syndromes and other clinical settings. These observations strengthened the hypothesis of additional, so-called pleiotropic actions of statins. The investigators therefore sought to investigate how different lipid-lowering strategies (non-statin therapy, low-dose statin and high-dose statin) affects cellular composition of carotid plaque over a short-term period of three months. Specifically the investigators tried and dissect the LDL-C lowering impact on plaque cellular composition as compared to the lipid-independent contribution on plaque macrophage and smooth muscle cells.
NCT01053065 ↗ The Multicenter Atorvastatin Plaque Stabilization (MAPS) Study Completed University of Padua N/A 1969-12-31 The impact on cardiovascular events achieved by statin therapy seems to be mostly attributable to the cholesterol-lowering effect with a highly debated contribution of the lipid-independent pleiotropic effects. However, a short-term benefit has been documented for patients treated with statins in acute coronary syndromes and other clinical settings. These observations strengthened the hypothesis of additional, so-called pleiotropic actions of statins. The investigators therefore sought to investigate how different lipid-lowering strategies (non-statin therapy, low-dose statin and high-dose statin) affects cellular composition of carotid plaque over a short-term period of three months. Specifically the investigators tried and dissect the LDL-C lowering impact on plaque cellular composition as compared to the lipid-independent contribution on plaque macrophage and smooth muscle cells.
NCT01062269 ↗ A Single Research Site Bile Acid Sequestrant Acceptability (BASA) Scale Pilot Validation Study Completed Daiichi Sankyo Inc. Phase 4 2010-01-01 The purpose of the research study is (1) to rate the taste, texture, appearance, and mixability of 2 different doses of orange flavored cholestyramine compared to orange flavored Tang, (2) rank the importance of the taste, texture, appearance, and mixability when rating cholestyramine and Tang to determine the accuracy and usefulness of a taste test questionnaire.
NCT01062269 ↗ A Single Research Site Bile Acid Sequestrant Acceptability (BASA) Scale Pilot Validation Study Completed Daiichi Sankyo, Inc. Phase 4 2010-01-01 The purpose of the research study is (1) to rate the taste, texture, appearance, and mixability of 2 different doses of orange flavored cholestyramine compared to orange flavored Tang, (2) rank the importance of the taste, texture, appearance, and mixability when rating cholestyramine and Tang to determine the accuracy and usefulness of a taste test questionnaire.
NCT01062269 ↗ A Single Research Site Bile Acid Sequestrant Acceptability (BASA) Scale Pilot Validation Study Completed Provident Clinical Research Phase 4 2010-01-01 The purpose of the research study is (1) to rate the taste, texture, appearance, and mixability of 2 different doses of orange flavored cholestyramine compared to orange flavored Tang, (2) rank the importance of the taste, texture, appearance, and mixability when rating cholestyramine and Tang to determine the accuracy and usefulness of a taste test questionnaire.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for QUESTRAN

Condition Name

Condition Name for QUESTRAN
Intervention Trials
DIABETES 2
Healthy 2
Primary Biliary Cirrhosis 1
DIABETIC NEUROPATHY 1
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Condition MeSH

Condition MeSH for QUESTRAN
Intervention Trials
Cholestasis, Intrahepatic 1
Neoplasms, Plasma Cell 1
Cholestasis 1
Multiple Myeloma 1
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Clinical Trial Locations for QUESTRAN

Trials by Country

Trials by Country for QUESTRAN
Location Trials
United States 6
Malaysia 3
Chile 2
France 1
Italy 1
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Trials by US State

Trials by US State for QUESTRAN
Location Trials
California 2
Kentucky 2
North Carolina 1
Michigan 1
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Clinical Trial Progress for QUESTRAN

Clinical Trial Phase

Clinical Trial Phase for QUESTRAN
Clinical Trial Phase Trials
Phase 4 3
Phase 3 1
Phase 2 1
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Clinical Trial Status

Clinical Trial Status for QUESTRAN
Clinical Trial Phase Trials
Completed 5
Recruiting 2
Unknown status 1
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Clinical Trial Sponsors for QUESTRAN

Sponsor Name

Sponsor Name for QUESTRAN
Sponsor Trials
National Cancer Institute (NCI) 2
City of Hope Medical Center 2
Daiichi Sankyo Inc. 2
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Sponsor Type

Sponsor Type for QUESTRAN
Sponsor Trials
Other 14
Industry 6
NIH 2
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