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Last Updated: November 13, 2024

CLINICAL TRIALS PROFILE FOR REGADENOSON


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All Clinical Trials for REGADENOSON

Trial ID Title Status Sponsor Phase Start Date Summary
NCT00208299 ↗ ADVANCE MPI 1: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI) Completed Astellas Pharma US, Inc. Phase 3 2003-10-01 Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. The investigational drug, regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist, the receptor responsible for coronary vasodilation, and is being studied for potential use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies. This study will compare the safety and efficacy of regadenoson to that of Adenoscan in detecting reversible myocardial perfusion defects.
NCT00208299 ↗ ADVANCE MPI 1: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI) Completed Gilead Sciences Phase 3 2003-10-01 Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. The investigational drug, regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist, the receptor responsible for coronary vasodilation, and is being studied for potential use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies. This study will compare the safety and efficacy of regadenoson to that of Adenoscan in detecting reversible myocardial perfusion defects.
NCT00208312 ↗ ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI) Completed Astellas Pharma US, Inc. Phase 3 2004-04-01 Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. The investigational drug, regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist, the receptor responsible for coronary vasodilation, and is being studied for potential use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies. This study will compare the safety and efficacy of regadenoson to that of Adenoscan in detecting reversible myocardial perfusion defects.
NCT00208312 ↗ ADVANCE MPI 2: Study of Regadenoson Versus Adenoscan® in Patients Undergoing Myocardial Perfusion Imaging (MPI) Completed Gilead Sciences Phase 3 2004-04-01 Adenoscan® (adenosine) is an approved pharmacological stress agent indicated as an adjunct to thallium-201 myocardial perfusion scintigraphy in patients unable to exercise adequately. The investigational drug, regadenoson (CVT-3146) is a selective A2A adenosine receptor agonist, the receptor responsible for coronary vasodilation, and is being studied for potential use as a pharmacologic stress agent in myocardial perfusion imaging (MPI) studies. This study will compare the safety and efficacy of regadenoson to that of Adenoscan in detecting reversible myocardial perfusion defects.
NCT00763035 ↗ Comparison of Dobutamine and Regadenoson Stress Cardiac Magnetic Resonance (MR) Terminated Astellas Pharma US, Inc. Early Phase 1 2009-01-01 The goal of this research is to determine the utility of Regadenoson (Lexiscan)for use as an imaging agent with cardiac MR. If found useful, it will help us establish a protocol for regadenoson stress MR perfusion (Regadenoson stress test with cardiac MR).The investigators will compare regadenoson with dobutamine so each participant will undergo two studies. A cardiac MR stress test with regadenoson and with dobutamine. The investigators participants will include patients with history of COPD and Asthma, so it will also help us determine feasibility of Regadenoson in these patient's subgroups.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for REGADENOSON

Condition Name

Condition Name for REGADENOSON
Intervention Trials
Coronary Artery Disease 25
Myocardial Ischemia 4
Coronary Artery Disease (CAD) 3
Asthma 2
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Condition MeSH

Condition MeSH for REGADENOSON
Intervention Trials
Coronary Artery Disease 35
Myocardial Ischemia 33
Coronary Disease 29
Ischemia 6
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Clinical Trial Locations for REGADENOSON

Trials by Country

Trials by Country for REGADENOSON
Location Trials
United States 168
Argentina 2
Netherlands 2
United Kingdom 2
Italy 1
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Trials by US State

Trials by US State for REGADENOSON
Location Trials
Illinois 14
California 13
Maryland 10
Missouri 9
Massachusetts 8
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Clinical Trial Progress for REGADENOSON

Clinical Trial Phase

Clinical Trial Phase for REGADENOSON
Clinical Trial Phase Trials
Phase 4 17
Phase 3 5
Phase 2 8
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Clinical Trial Status

Clinical Trial Status for REGADENOSON
Clinical Trial Phase Trials
Completed 36
Recruiting 9
Terminated 5
[disabled in preview] 6
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Clinical Trial Sponsors for REGADENOSON

Sponsor Name

Sponsor Name for REGADENOSON
Sponsor Trials
Astellas Pharma Inc 15
Astellas Pharma US, Inc. 11
Astellas Pharma Global Development, Inc. 6
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Sponsor Type

Sponsor Type for REGADENOSON
Sponsor Trials
Other 77
Industry 43
NIH 6
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