Study to Determine the Amount of Glycopyrrolate Absorbed in the Lungs After Taking the Medicine With a eFlow Nebulizer and Seebri® Breezhaler® With and Without Activated Charcoal in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Di
Completed
Sunovion Respiratory Development Inc.
Phase 1
2015-10-01
The purpose of this research study is to determine the amount of medicine absorbed in the
lungs following dosing via eFlow nebulizer and Seebri® Breezhaler® with and without activated
charcoal in subjects with moderate to severe chronic obstructive pulmonary disease (COPD).
Duration of Long Acting Muscarinic Antagonist (LAMA) Bronchoprotection Against Methacholine Challenge
Completed
University of Saskatchewan
Phase 4
2015-11-01
The study will assess the duration of protection of single doses of 2 different long acting
muscarinic antagonists against methacholine induced bronchoconstriction.
Effect of a LAMA and a uLABA on the Methacholine Dose-response Curve
Completed
University of Saskatchewan
Phase 4
2016-10-01
The study will assess the effects of two drugs, glycopyrronium and indacaterol, taken either
as monotherapy or in combination, on the methacholine dose-response curve. This will allow
for further elucidation of the mechanisms of each drug in human participants.
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