Treatment of Agitation/Psychosis in Dementia/Parkinsonism (TAP/DAP)
Completed
National Institute on Aging (NIA)
Phase 4
2002-07-01
The primary aim of this study is to determine the safety and efficacy of quetiapine
(Seroquel) for the treatment of psychosis and/or agitation in patients with primary dementia
complicated by coexistent parkinsonism, or patients with Parkinson's disease with dementia
[PDD] who have episodes of agitation or psychosis. The secondary aim is to determine the
safety and tolerability, particularly the influence on parkinsonism, of quetiapine when used
to treat psychosis and/or agitation in patients with dementia complicated by coexistent
parkinsonism.
This study will evaluate the effectiveness of switching medications in decreasing
schizophrenia symptoms in individuals who are currently taking an antipsychotic medication
for the treatment of schizophrenia.
This study will evaluate the effectiveness of switching medications in decreasing
schizophrenia symptoms in individuals who are currently taking an antipsychotic medication
for the treatment of schizophrenia.
Treatment and Outcome of Early Onset Bipolar Disorder
Completed
National Institute of Mental Health (NIMH)
Phase 4
2002-08-01
This study will compare the effectiveness in the maintenance of continuing adjunctive
atypical antipsychotic medication compared to traditional mood stabilizer(s) alone in the
maintenance treatment of adolescents with bipolar disorder.
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