CLINICAL TRIALS PROFILE FOR SERTRALINE HYDROCHLORIDE
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All Clinical Trials for SERTRALINE HYDROCHLORIDE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00000321 ↗ | Methamphetamine Abuse Treatment in Patients With AIDS - 1 | Completed | Friends Research Institute, Inc. | Phase 4 | 1996-10-01 | The purpose of this study is to evaluate the efficacy of desipramine, sertraline, and placebo on methamphetamine dependent gay men with AIDS. |
| NCT00000321 ↗ | Methamphetamine Abuse Treatment in Patients With AIDS - 1 | Completed | National Institute on Drug Abuse (NIDA) | Phase 4 | 1996-10-01 | The purpose of this study is to evaluate the efficacy of desipramine, sertraline, and placebo on methamphetamine dependent gay men with AIDS. |
| NCT00000378 ↗ | Antidepressant Treatment of Melancholia in Late Life | Completed | National Institute of Mental Health (NIMH) | Phase 4 | 1997-07-01 | The purpose of this study is to compare the safety and effectiveness of a select serotonin re-uptake inhibitor (SSRI, sertraline) and a tricyclic antidepressant (TCA, nortriptyline) in outpatients over the age of 60 who have major depression. SSRIs are effective in the treatment of major depression. However, there is also evidence that SSRIs may be significantly less effective than TCAs for patients with late-life major depression with melancholia. Since SSRIs seem to be easier to take than TCAs and are more widely prescribed, it is important to determine which of these types of antidepressants works best to treat these patients. Patients will be assigned randomly to receive either sertraline (a SSRI) or nortriptyline (a TCA) for 12 weeks. Patients will be monitored for symptoms, side effects, and quality of life. If a patient responds to treatment, he/she will participate in a 6-month continuation phase in which he/she will continue to receive the same medication. An individual may be eligible for this study if he/she: Has unipolar major depression (with some exceptions) and is over 60 years old. |
| NCT00000378 ↗ | Antidepressant Treatment of Melancholia in Late Life | Completed | New York State Psychiatric Institute | Phase 4 | 1997-07-01 | The purpose of this study is to compare the safety and effectiveness of a select serotonin re-uptake inhibitor (SSRI, sertraline) and a tricyclic antidepressant (TCA, nortriptyline) in outpatients over the age of 60 who have major depression. SSRIs are effective in the treatment of major depression. However, there is also evidence that SSRIs may be significantly less effective than TCAs for patients with late-life major depression with melancholia. Since SSRIs seem to be easier to take than TCAs and are more widely prescribed, it is important to determine which of these types of antidepressants works best to treat these patients. Patients will be assigned randomly to receive either sertraline (a SSRI) or nortriptyline (a TCA) for 12 weeks. Patients will be monitored for symptoms, side effects, and quality of life. If a patient responds to treatment, he/she will participate in a 6-month continuation phase in which he/she will continue to receive the same medication. An individual may be eligible for this study if he/she: Has unipolar major depression (with some exceptions) and is over 60 years old. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
Clinical Trial Conditions for SERTRALINE HYDROCHLORIDE
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Clinical Trial Progress for SERTRALINE HYDROCHLORIDE
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Clinical Trial Sponsors for SERTRALINE HYDROCHLORIDE
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