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Last Updated: November 2, 2024

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CLINICAL TRIALS PROFILE FOR SIMBRINZA


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All Clinical Trials for SIMBRINZA

Trial ID Title Status Sponsor Phase Start Date Summary
NCT01937299 ↗ Effect of SIMBRINZA® Suspension as an Added Therapy to TRAVATAN Z® Completed Alcon Research Phase 4 2013-10-01 The purpose of this study is to demonstrate the additive effect of brinzolamide 1%/brimonidine 0.2% (SIMBRINZA® suspension) in subjects with either open angle glaucoma or ocular hypertension who are currently on a prostaglandin analogue (PGA) monotherapy (TRAVATAN Z®).
NCT01937312 ↗ Effect of SIMBRINZA® Suspension as an Added Therapy to a Prostaglandin Analogue Completed Alcon Research Phase 4 2013-10-01 The purpose of this study is to demonstrate the additive effect of brinzolamide 1%/brimonidine 0.2% (SIMBRINZA® suspension) in subjects with either open angle glaucoma or ocular hypertension who are currently on a prostaglandin analogue (PGA) monotherapy.
NCT01978600 ↗ Evaluation of Intraocular Pressure Using Simbrinza™ in Patients With Open-Angle Glaucoma or Ocular Hypertension Completed Alcon Research Phase 4 2013-10-01 The purpose of this study is to evaluate intraocular pressure (IOP) over a 24-hour period using Simbrinza™ topical ophthalmic suspension.
NCT02167035 ↗ Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID) Completed Allergan Phase 4 2014-08-01 To compare Combigan Two Times Daily (BID) vs Simbrinza Three Times Daily (TID) in subjects currently being treated with Latanoprost for Open-Angle Glaucoma or Ocular Hypertension. Both of these drugs are currently FDA approved as combination therapy for patients with Open-Angle Glaucoma or Ocular Hypertension. The purpose of this clinical trial would be to assess which treatment, if either, is superior in lowering intraocular pressure (IOP). A secondary objective is to assess the tolerability of each drug.
NCT02167035 ↗ Comparison of Combigan Two Times Daily (BID) Versus Simbrinza Three Times Daily (TID) Completed Cornerstone Health Care, PA Phase 4 2014-08-01 To compare Combigan Two Times Daily (BID) vs Simbrinza Three Times Daily (TID) in subjects currently being treated with Latanoprost for Open-Angle Glaucoma or Ocular Hypertension. Both of these drugs are currently FDA approved as combination therapy for patients with Open-Angle Glaucoma or Ocular Hypertension. The purpose of this clinical trial would be to assess which treatment, if either, is superior in lowering intraocular pressure (IOP). A secondary objective is to assess the tolerability of each drug.
NCT02419508 ↗ SIMBRINZA® Suspension BID as an Adjunctive to Prostaglandin Analogue (PGA) Completed Alcon Research Phase 4 2015-08-07 The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of brinzolamide 1%/brimonidine 0.2% (dosed twice per day (BID)) when added to a prostaglandin analogue (PGA) in subjects with open-angle glaucoma or ocular hypertension.
NCT02730871 ↗ Safety and Efficacy of SIMBRINZA® BID as an Adjunctive to DUOTRAV® Terminated Alcon Research Phase 4 2016-06-24 The purpose of this study is to evaluate the additive intraocular pressure (IOP) lowering effect of Brinzolamide 1%/Brimonidine 0.2% (SIMBRINZA®) dosed twice daily (BID) when added to Travoprost 0.004%/Timolol 0.5% (DUOTRAV®) in subjects with open-angle glaucoma or ocular hypertension.
>Trial ID >Title >Status >Phase >Start Date >Summary

Clinical Trial Conditions for SIMBRINZA

Condition Name

Condition Name for SIMBRINZA
Intervention Trials
Ocular Hypertension 7
Glaucoma 3
Open-angle Glaucoma 3
Open Angle Glaucoma 2
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Condition MeSH

Condition MeSH for SIMBRINZA
Intervention Trials
Glaucoma 7
Ocular Hypertension 7
Glaucoma, Open-Angle 6
Hypertension 3
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Clinical Trial Locations for SIMBRINZA

Trials by Country

Trials by Country for SIMBRINZA
Location Trials
United States 5
Korea, Republic of 1
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Trials by US State

Trials by US State for SIMBRINZA
Location Trials
Texas 3
North Carolina 2
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Clinical Trial Progress for SIMBRINZA

Clinical Trial Phase

Clinical Trial Phase for SIMBRINZA
Clinical Trial Phase Trials
Phase 4 8
Phase 3 1
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Clinical Trial Status

Clinical Trial Status for SIMBRINZA
Clinical Trial Phase Trials
Completed 7
Terminated 1
Recruiting 1
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Clinical Trial Sponsors for SIMBRINZA

Sponsor Name

Sponsor Name for SIMBRINZA
Sponsor Trials
Alcon Research 6
Allergan 1
Cornerstone Health Care, PA 1
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Sponsor Type

Sponsor Type for SIMBRINZA
Sponsor Trials
Industry 9
Other 1
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