CLINICAL TRIALS PROFILE FOR SOLODYN
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All Clinical Trials for SOLODYN
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00473083 ↗ | Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer | Completed | Hoffmann-La Roche | Phase 2 | 2009-01-01 | The purpose of this trial is to determine if rash caused by erlotinib can be successfully treated and if so to determine the optimal treatment approach. Hypothesis: Hypothesis 1: If the incidence of rash is 50% while on erlotinib, prophylactic monotherapy with minocycline can prevent occurrence in 50% of these patients. Hypothesis 2: Treatment of rash is successful in improving rash by at least one Grade in 80% of patients. Hypothesis 3: In patients with untreated rash, the rash will be self-limiting in 25% of patients, and 65% will be grade 1, 2A, and 2b. Ten percent will be grade 3 requiring treatment with monotherapy intervention. |
| NCT00473083 ↗ | Systemic and Topical Treatments for Rash Secondary to Erlotinib in Lung Cancer | Completed | British Columbia Cancer Agency | Phase 2 | 2009-01-01 | The purpose of this trial is to determine if rash caused by erlotinib can be successfully treated and if so to determine the optimal treatment approach. Hypothesis: Hypothesis 1: If the incidence of rash is 50% while on erlotinib, prophylactic monotherapy with minocycline can prevent occurrence in 50% of these patients. Hypothesis 2: Treatment of rash is successful in improving rash by at least one Grade in 80% of patients. Hypothesis 3: In patients with untreated rash, the rash will be self-limiting in 25% of patients, and 65% will be grade 1, 2A, and 2b. Ten percent will be grade 3 requiring treatment with monotherapy intervention. |
| NCT01048983 ↗ | Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC) | Withdrawn | National Cancer Institute (NCI) | Phase 1/Phase 2 | 1969-12-31 | The goal of this clinical research study is to compare armodafinil, bupropion, curcumin, and minocycline when given alone or in combination to learn which is better for controlling symptoms, such as the side effects of chemoradiation, when given to treat lung cancer. |
| NCT01048983 ↗ | Reducing Symptom Burden - Non Small Cell Lung Cancer (NSCLC) | Withdrawn | M.D. Anderson Cancer Center | Phase 1/Phase 2 | 1969-12-31 | The goal of this clinical research study is to compare armodafinil, bupropion, curcumin, and minocycline when given alone or in combination to learn which is better for controlling symptoms, such as the side effects of chemoradiation, when given to treat lung cancer. |
| NCT01173692 ↗ | Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study. | Completed | National Cancer Institute (NCI) | Phase 2 | 2010-07-22 | The goal of this clinical research study is to learn if minocycline can reduce the symptoms reported by patients with oropharynx cancer, nasopharynx cancer, or unknown primary cancer of head and neck, who receive treatment with radiation therapy. |
| NCT01173692 ↗ | Minocycline for Reduction of Radiation Therapy Treatment-Related Symptom Burden in Oropharynx Cancer: A Randomized Study. | Completed | M.D. Anderson Cancer Center | Phase 2 | 2010-07-22 | The goal of this clinical research study is to learn if minocycline can reduce the symptoms reported by patients with oropharynx cancer, nasopharynx cancer, or unknown primary cancer of head and neck, who receive treatment with radiation therapy. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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