Sorafenib in Treating Patients With Metastatic or Recurrent Prostate Cancer
Completed
National Cancer Institute (NCI)
Phase 2
2004-07-21
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking the enzymes necessary for
their growth.
PURPOSE: This phase II trial is studying the effectiveness of sorafenib in treating patients
who have metastatic or recurrent prostate cancer that has not responded to previous hormone
therapy.
Sorafenib in Treating Patients With Metastatic or Recurrent Prostate Cancer
Completed
NCIC Clinical Trials Group
Phase 2
2004-07-21
RATIONALE: Sorafenib may stop the growth of tumor cells by blocking the enzymes necessary for
their growth.
PURPOSE: This phase II trial is studying the effectiveness of sorafenib in treating patients
who have metastatic or recurrent prostate cancer that has not responded to previous hormone
therapy.
Sorafenib in Treating Patients With Recurrent or Progressive Malignant Glioma
Completed
National Cancer Institute (NCI)
Phase 1
2004-12-01
This phase I trial is studying the side effects and best dose of sorafenib in treating
patients with recurrent or progressive malignant glioma. Sorafenib may stop the growth of
tumor cells by stopping blood flow to the tumor and by blocking the enzymes necessary for
their growth.
Sorafenib in Treating Patients With Persistent or Recurrent Ovarian Epithelial or Peritoneal Cancer
Completed
Gynecologic Oncology Group
Phase 2
2004-10-01
Sorafenib may stop the growth of tumor cells by stopping blood flow to the tumor and by
blocking the enzymes necessary for their growth. This phase II trial is studying how well
sorafenib works in treating patients with persistent or recurrent ovarian epithelial or
peritoneal cancer.
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