CLINICAL TRIALS PROFILE FOR SOTALOL HYDROCHLORIDE
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All Clinical Trials for SOTALOL HYDROCHLORIDE
| Trial ID | Title | Status | Sponsor | Phase | Start Date | Summary |
|---|---|---|---|---|---|---|
| NCT00000464 ↗ | Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) | Completed | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 | 1987-04-01 | To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest. |
| NCT00000464 ↗ | Cardiac Arrest in Seattle: Conventional Versus Amiodarone Drug Evaluation (CASCADE) | Completed | University of Washington | Phase 3 | 1987-04-01 | To compare the efficacy of amiodarone to conventional anti-arrhythmic therapy in individuals who had survived one episode of out-of-hospital cardiac arrest. |
| NCT00000518 ↗ | Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) | Completed | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 | 1985-07-01 | To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death. |
| NCT00000518 ↗ | Electrophysiologic Study Versus Electrocardiographic Monitoring (ESVEM) | Completed | University of Utah | Phase 3 | 1985-07-01 | To determine whether electrophysiologic study (EPS) or Holter monitoring (HM) was the better method for selecting effective long-term antiarrhythmic drug therapy in patients with sustained ventricular tachycardia, ventricular fibrillation, or an episode of aborted sudden death. |
| NCT00000531 ↗ | Antiarrhythmics Versus Implantable Defibrillators (AVID) | Completed | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 | 1992-09-01 | To evaluate if use of an implantable cardiac defibrillator (ICD) results in reduction in total mortality, when compared with conventional pharmacological therapy, in patients resuscitated from sudden cardiac death who are otherwise at very high risk of mortality from arrhythmic causes. |
| NCT00000556 ↗ | Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) | Completed | National Heart, Lung, and Blood Institute (NHLBI) | Phase 3 | 1995-03-01 | To compare two standard treatment strategies for atrial fibrillation: ventricular rate control and anticoagulation vs. rhythm control and anticoagulation. |
| NCT00007605 ↗ | Comparing the Effects of Amiodarone, Sotalol, and Placebo in Maintaining Sinus Rhythm in Patients With Atrial Fibrillation Converted to Sinus Rhythm | Completed | US Department of Veterans Affairs | Phase 3 | 1998-04-01 | Atrial fibrillation is the most frequently occurring cardiac arrhythmia, with 1.0-1.5 million cases annually. It is a risk factor for congestive heart failure, and stroke, 75,000 cases of the latter occurring annually in patients with atrial fibrillation. The safety of the most widely used antiarrhythmic agent for this group of patients, quinidine, has been called into question. This study seeks to determine whether two other agents, amiodarone and sotalol, are safe and effective treatments for patients with atrial fibrillation. |
| >Trial ID | >Title | >Status | >Sponsor | >Phase | >Start Date | >Summary |
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