Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Completed
National Cancer Institute (NCI)
Phase 1
1998-06-01
RATIONALE: Monoclonal antibodies can find and locate tumor cells and either kill them or
deliver tumor-killing substances to them without harming normal cells. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. Combining more than one drug and combining chemotherapy with monoclonal antibody therapy
may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy plus
combination chemotherapy in treating patients with advanced colorectal cancer.
Monoclonal Antibody Therapy Plus Combination Chemotherapy in Treating Patients With Advanced Colorectal Cancer
Completed
Memorial Sloan Kettering Cancer Center
Phase 1
1998-06-01
RATIONALE: Monoclonal antibodies can find and locate tumor cells and either kill them or
deliver tumor-killing substances to them without harming normal cells. Drugs used in
chemotherapy use different ways to stop tumor cells from dividing so they stop growing or
die. Combining more than one drug and combining chemotherapy with monoclonal antibody therapy
may kill more tumor cells.
PURPOSE: Phase I trial to study the effectiveness of monoclonal antibody therapy plus
combination chemotherapy in treating patients with advanced colorectal cancer.
Phase II Study of Carmustine, Streptozocin, and Mercaptopurine for Refractory or Recurrent Brain Neoplasms
Completed
Emory University
Phase 2
1996-08-01
OBJECTIVES:
I. Assess the clinical response of patients with refractory or recurrent brain neoplasms
treated with carmustine, streptozocin, and mercaptopurine.
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